A 21-year-old girl of Britain collapsed on the dance floor itself after downing Red Bull and also a vodka-based drink. The caffeine in both could have triggered a rare heart condition.
Chloe Leach, had drunk around four cans of the energy drink and several VKs - a vodka based drink which also contains caffeine - when she suddenly fell to the floor in the Sugarmill club in Hull, East Yorks, on September 30 last year.
Miss Leach, a third-year social work student, of Cottingham, East Yorks., died at the scene despite efforts from staff and paramedics to revive her.
She had been diagnosed with epilepsy in 2001 after suffering fits and seizures, was believed to have suffered from QT Syndrome - a condition which affects the electric activity in the heart.
She also had an abnormally large heart, and the doctor who carried out the post-mortem felt it was "probable" that the caffeine had raised her QT Syndrome level to "abnormal."
Dr Ian Scott, a consultant neuropathologist, told an inquest Monday: "On the basis of probability, her epilepsy, the QT, her abnormal heart and the the high levels of caffeine found, the most likely cause of death was a cardiac arrhythmia due to underlying QT Syndrome.
"I excluded drugs as a cause - the only drugs she had taken was her anti-epilepsy medication. QT sufferers are prone to sudden arrests, the threat of which may not be detected during normal scans."
Miss Leach's mum Tina had suffered a heart attack some time ago and her cousin had previously died suddenly, which meant her entire family were scanned to search for defects, the hearing was told.
Although she was never officially diagnosed with the syndrome, she had a QT "upper limit" which Dr Scott added could have increased in the years following her scans.
He said: "The QT levels may have grown over a few years, or it may have been artificially pushed over the limit by caffeine."
In the early hours of the club's student night, just before Miss Leach collapsed at around 3am, guest DJ Danny Latimer was hospitalised claiming his drink had been spiked, leading to rumours that she had been the victim of a similar crime.
But it emerged that the former 'Shipwrecked' star had been charged with possessing Class C drugs and perverting the course of justice.
A medical report confirmed that Miss Leach had no drugs in her system other than her anti-epilepsy medication, Telegraph reported.
Miss Leach's mum Tina, giving evidence, said: "Chloe was careful regarding her consumption of caffeine. She would drink Red Bull occasionally and was aware it contained caffeine.
"My concern is that we will never ever be able to prove she had QT Syndrome. We will always doubt the circumstances surrounding Chloe that night. I accept that we don't have any evidence she had any substance in her blood, but the description we have of what happened to the DJ is so similar to what happened to her.
"It seems too much of a coincidence and there are so many things that don't add up."
Ellouise Maxwell, who lived with Miss Leache and was also on her course at the University of Lincoln, Hull Campus, said: "She was a happy, funny, optimistic, positive girl. She was the top student out of 90 on the course."
She added that hours before the night out on which she died, Miss Leach had complained of felling dizzy during a lecture but put this down to period pains.
Later she went to a friend's house, where she drunk a bottle of wine together with two cans of Red Bull because she "felt tired". She then drank approximately two more cans of the energy drink and a couple of VK drinks.
Another friend, Lorna Green, said: "I saw Chloe fall. I thought she had tripped up. She was being sick but was not having a fit."
Dr Stephen Morley, a consultant pathologist, said of Miss Leach's Red Bull consumption:"She may have had as little as two cans, she may have had as many as six. It was more probably about four."
He added that a normal cup of coffee has 40 milligrammes of caffeine, and Red Bull has 80 milligrammes in each can.
The family's GP confirmed that Chloe had suffered her first fit in 1991 and also fainted and had a seizure in two separate incidents in 2001. She was diagnosed with epilepsy, and had one further seizure in October 2002, but after that had not suffered again with fits.
Geoffrey Saul, the coroner, ruled that Miss Leach died of natural causes.
He said: "The most likely trigger was Long QT Syndrome. Dr Ian Scott, who conducted the post-mortem into her death, accepted she had never been diagnosed with this, but he reasoned this could have grown over the years.
"She had been diagnosed as being in the upper limit, and her ingestion of caffeine in the Red Bull may have led her to move above the threshold to abnormal."
After the inquest, Miss Leach's family said in a statement: "Chloe was a very promising, delightful young student of impeccable character and soon to be qualified social worker. Not only is Chloe's loss a heartbreaking loss to our family, Chloe is a loss to society too."