Researchers at the University of Michigan have succeeded in creating artificial bone marrow that is capable of continuously generating new red and white blood cells. The discovery may help simplify procedures for drug testing and immune system defects.
Project leader Nicholas Kotov, a professor in the U-M departments of Chemical Engineering, has revealed that the marrow is not made to be implanted in the body.
Bone Marrow Aspiration and Biopsy-Indications-Common Sites-Performed-Risks-FAQs
Bone marrow biopsy and aspiration is the removal of some bone marrow tissue for diagnosis and management of cancers of blood cells and multiple myeloma.
Bone marrow biopsy and aspiration is the removal of some bone marrow tissue for diagnosis and management of cancers of blood cells and multiple myeloma.
"This is the first successful artificial bone marrow. It has two of the essential functions of bone marrow. It can replicate blood stem cells and produce B cells. The latter are the key immune cells producing antibodies that are important to fighting many diseases," Kotov said.
The researchers said that the new artificial marrow could help determine how a new drug at certain potencies would affect bone marrow function, and thereby assist in drug development and catch severe side effects before human drug trials.
Bone Marrow Transplantation
Animation and slides providing graphic explanation of Bone Marrow Transplantation (BMT)/Stem Cell Transplantation that is done for leukemia and other blood-related disorders.
Animation and slides providing graphic explanation of Bone Marrow Transplantation (BMT)/Stem Cell Transplantation that is done for leukemia and other blood-related disorders.
With a view to seeing whether the substance would behave like real bone marrow, the researchers implanted it in mice with immune deficiencies.
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In a new study, scientists have found that stem cells from bone marrow may act as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized
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An article on this research work has been published in the online edition of the journal Biomaterials.
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Stem Cell 'Living Bandage' can Help Heal Knee Injury
Scientists at Bristol University have managed to grow a living bandage from a patient's own stem cells in a bid to heal a common sporting knee injury.
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