Anti-obesity Drugs Provide Short-term Health Benefits

by Trilok Kapur on  March 19, 2010 at 1:16 PM Drug News
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 Anti-obesity Drugs Provide Short-term Health Benefits
Anti-obesity drugs fall short of providing long lasting health benefits, researchers have pointed out.

Experts at the University of Liverpool debated the drugs handled the biological consequences of obesity since most developers focused primarily on weight loss as their end goal.

Dr Jason Halford, Reader in Appetite and Obesity at the University of Liverpool, and his co-authors argued the important psychological causes that lead to over consumption and weight gain were left ignored.

Dr Halford said: "Anti-obesity drugs haven't successfully tackled the wider issues of obesity because they've been focused predominantly on weight loss. Obesity is the result of many motivational factors that have evolved to encourage us to eat, not least our susceptibility to the attractions of food and the pleasures of eating energy rich foods - factors which are, of course, all too effectively exploited by food manufacturers.

"As psychological factors are critical to the development of obesity, drug companies should take them into consideration when designing new drug therapies. We've learned a great deal about the neurochemical systems that govern processes like the wanting and liking of food, and it's time to exploit that knowledge to help people manage their eating behavior."

Professor Tim Kirkham, an authority on the biopsychology of appetite at the University of Liverpool, added: "Novel, effective anti-obesity treatments must address these different factors. We need to identify drugs that can selectively affect the desire to eat, the enjoyment of eating, fullness and satisfaction. Interventions designed specifically to modulate these processes could help reduce the aversive experience of dieting, and maximize an individual's capacity to successfully gain control over their appetite. Currently, we know little about the behavioural effects of anti-obesity drugs under development, and so we have little indication whether these new treatment address the underlying causes of obesity."

The study has been published in Nature Reviews Endocrinology.

Source: ANI

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Yep! They do pay. Obestrin works pretty well too. I lost 27 pounds and feel better. Good stuff!

Hi I was Just wanting some info on the obestrin.what are some of the side effects? how do you get this pill?It looks like you started taking a few months ago, just wandering how it is going for you, any info would be great , thanks

VP- I am sending in my money today... from the research I found it seems they do pay the $350 but I am more considered about the weight loss than the money.. have you lost anything yet? How long did it take you to get the pills?


I personally know that there is an effective anti-obesity drug on the horizon. My elder sister had struggled with weight issues most of her life.

She was in a clinical trial of AVT-12 and lost nearly 100 pounds during the year the trial lasted! She did some walking that was recommended, but most of her benefits came from the drug they tested on her. No side effects or other problems.

They call it Obestrin now. I've been lucky and don't have more than 10 pounds or so of excess weight, but I believe that it may have saved her life!


I was anxious to join this study but first want to make sure it is legitimate. There are no phone numbers listed anywhere, but just the e-mail address and where you should mail the money. Please help me by telling me if you went through the website and contacted anyone there.

I thank and appreciate you for letting me know.

Hi ckrice- I am also interested in joing the study. Have you heard anything? I applied but have not got a response yet.


I'm in the study. I have no idea how legitimate it is. I don't have any phone numbers to reach them. I did receive the 180 pills. Only time will tell if I actually get paid the $350 as promised at the end of 6 moonths.


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