Stents used to arrest the growth of tissues in arteries can also have life threatening side effects like blood clots and heart attacks.
Now, researchers have developed a computer model that explains why those drugs released from stents accumulate in the arteries and cause blood clots.
Safer Stents on the Anvil Thanks to Novel Computer Model
New computer models to predict physiologically realistic drug delivery patterns from stents in branched arterial vessels have been developed by researchers at Massachusetts Institute of Technology.
New computer models to predict physiologically realistic drug delivery patterns from stents in branched arterial vessels have been developed by researchers at Massachusetts Institute of Technology.
The findings explain why drugs can pile up in certain areas, depending on where the stent is placed relative to forks in the artery.
"By observing the arterial drug distribution patterns for various settings, we understood that drug released from the stent does not reach uniformly to all regions of the vessel and this non-uniformity depends on where the stent is placed in the artery as well as the blood flow that is entering the vessel," said Edelman.
Poor Clinical Outcomes Seen With Higher Carotid Arterial Stenting Rates
Increased use of carotid arterial stenting (CAS) procedures to treat carotid stenosis is associated with higher rates of mortality and adverse clinical outcomes
Increased use of carotid arterial stenting (CAS) procedures to treat carotid stenosis is associated with higher rates of mortality and adverse clinical outcomes
It also raises the possibility of designing individualized stents for patients. It could aid the FDA in its approval process for stents.
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Abbotts Drug Eluting Stents Receive Europe Nod for Treating Diabetics
Abbott’s drug eluting stents have received additional new CE Markings (Conformité Européenne), covering the treatment of patients with diabetes.
Abbott’s drug eluting stents have received additional new CE Markings (Conformité Européenne), covering the treatment of patients with diabetes.
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For Heart Attack Patients, Drug-Eluting Stent More Efficient Than Bare-Metal Stents
A new study has shown that the use of a drug-eluting stent (paclitaxel) is safer and more effective than a bare-metal stent in heart attack patients.
A new study has shown that the use of a drug-eluting stent (paclitaxel) is safer and more effective than a bare-metal stent in heart attack patients.
