Skin
Smoking is associated with many dermatological conditions such as poor wound healing, acne, psoriasis, melanoma, squamous cell carcinoma and premature aging of the skin.
Smoking impairs the production of collagen and increases the formation of tropoelastin and matrix metalloproteinases. These compounds cause degradation of collagen, a protein responsible for skin firmness, elasticity and younger-looking skin.
This gives rise to signs of premature aging of the skin like fine lines, wrinkles, dark spots and dark circles.