News and Research on Genetics & Stem Cells

Cilium Could be Genetic Key to Common Diseases

Rare genetic disorders affecting the cilium have been discovered. The cilium is characterized by a number of health problems, including common conditions like diabetes, kidney failure, and liver fibrosis. These findings were published today in the ...

Study Details Sequencing of Full Human Genomes

The details of sequencing of 64 full human genomes by the team of researchers at the University of Maryland School of Medicine (UMSOM), published in the journal Science , includes individuals from around the world. These details can better capture ...

World-First Fabry Disease Treated With Gene Therapy

Fabry disease patients were treated for the first time with gene therapy. Researchers say that the treatment is working and safe, revealed a world-first Canadian pilot study. The Canadian research team was the first to use gene therapy in 2017 ...

New Gene-editing Tool Discovered

A new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time has been discovered by University of Illinois Chicago researchers. CRISPR uses an enzyme called Cas9 that acts like scissors to ...

Genetic Testing Detects Uncommon Variants Incorrectly

Technology that is commonly used by commercial genetic testing companies is incorrect in detecting very rare variants, as per the study in the BMJ . After hearing of cases where women had surgery scheduled after wrongly being told they had ...

Genomic Medicine Helps Identify Cancer Mutations Responsive To Drugs

New personalized genomic medicine platforms that will help advance accelerate genomic medicine research and genome-informed drug discovery has been developed by researchers. Genomic medicine is the study of genes and their interaction with health. ...

CRISPR Technology Targets Human Genome's Complex Code

New genome editing tool targets the supporting players in a cell's nucleus that package DNA and aid gene expression. Rice bioengineer Isaac Hilton, postdoctoral researcher and lead author Jing Li and their colleagues programmed a modified ...

Gene Target Can Suppress Progression Of Age-Related Diseases

Senescence is a process by which a cell ages and permanently stops dividing but does not die. During aging, the senescent cells accumulate in organs and promote tissue dysfunction leading to numerous age-related diseases like cancer. The cells go ...

Genes Responsible for the Shape of Face Identified

Genes that assess the shape of a person's facial profile have been identified by a UCL-led research team. The analysis of data from more than 6,000 volunteers across Latin America was published in Science Advances . The researchers identified ...

Machine Learning Generates Human Genomes

Researchers have used machine learning to mine existing biobanks and generate chunks of human genomes which do not belong to real humans but have the characteristics of real genomes. The findings of the study are published in the ...

Stem Cell Therapy In Dogs Offer Hope In Human Diseases

Dogs remain faithful companions to humans ever since their domestication thousands of years ago. Although the improvements in veterinary medicine have increased the life expectancy of dogs, it has simultaneously invited the occurrence of chronic ...

Gene Editing Hold Potential to Correct Retinal Degenerations

Gene editing therapies, including CRISPR-Cas systems hold promise in correcting mutations that are responsible for inherited retinal degenerations. Technological advances in gene editing, continuing safety concerns, and strategies to overcome ...

Intestinal Stem Cell: New Approach To Treatment

The gut is known to play an important role in the regulation of the body's metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide. ...

DNA-editing Technique Shows Promise to Treat Progeria, Aging Disorder

A DNA-editing method called base editing helps extend mice's lifespan with the genetic variation linked to progeria. Progeria is a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life ...

Autism Symptoms Seen In Genetic Conditions

A study has determined that people with certain genetic conditions are likely to have significant symptoms of autism even if they do not meet all the diagnostic criteria. The research conducted at Cardiff University is published in journal The ...