Medindia LOGIN REGISTER
Medindia

Estimation of Risks of Genetic Counselling

Interesting Features about above inheritance includes

  • Males and females - equally affected 
  • 25% of offspring - Affected 
  • Horizontal transmission with chances of skipped generations is always present. 
  • Consanguinity between parents play a role in their condition 
  • The Traits are observed more commonly within smaller families. 

AUTOSOMAL DOMINANT 

Leprosy

a - affected chromosome with gene. 

Examples of the above type of Autosomal dominant inheritance includes.

   a) Adult polycystic kidney disease

b) Von - Hippele liadan ( VHL ) syndrome

  c) Papillary renal cell carcinoma

Advertisement

d) Wilm’s tumour. 

Intersting features about Autosomal Dominant inheritance includes the following. 

  • Males & females are equally affected. 
  • Vertical transmission - with an affected individual in each generation. 
  • Hamozygous dominant condition is often fatal. 
  • Prominent in larger families. 
  • Father to son transmission is possible 

Advertisement
Recommended Reading