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Chronic Myeloid Leukemia - Signs and Symptoms


Signs and Symptoms

Most CML patients are asymptomatic initially. They are accidentally diagnosed during a routine laboratory check. Symptoms appear as the disease progresses.

Patients with CML have no symptoms at diagnosis. At first, there are no signs or symptoms of CML. Many people come to understand that they have CML after a routine laboratory examination. CML must,however, be distinguished from a leukemoid reaction which will display similar charecteristics on a blood smear.

Common symptoms of CML are the following:

  • Anemia
  • Malaise and fatigue
  • Pale skin
  • Low- grade fever
  •  Decreased platelet count ( Thrombocytopenia)
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  • Increased platelet count (Thrombocytosis)
  • Increased susceptibility to infections,such as cold or flu
  • Easy bruising
  • Weight loss
  • Shortness of breath
  • Increased sweating especially night sweats
  • Swollen spleen leading to discomfort in the stomach area (Splenomegaly)
  • Painful bone and joints
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