Role of Hydrocortisone in Septic Shock

The role of corticosteroids in septic shock has always been controversial. Corticosteroids, which include drugs like hydrocortisone and fludrocortisone, reduce inflammation and help the body tide over stressful conditions. Two large landmark studies published in the New England Journal of Medicine evaluated the possible role of corticosteroids in the treatment of septic shock; their conclusions, however, were not entirely in sync.
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