Somatic Mutations of Genes in Rheumatoid Arthritis Patients

Mutations in the genes encoding immune function have been detected in CD8+ T-cells in rheumatoid arthritis patients in a study undertaken by the University of Helsinki and the Helsinki University Central Hospital, suggesting that such mutations might be contributing to the evolution of autoimmune diseases such as rheumatoid arthritis.

Rheumatoid arthritis associated with somatic mutations in effector T- cells
- Somatic mutations have been known to cause cancer
- Rheumatoid arthritis patients showed somatic mutations of genes affecting immune function

Rheumatoid Arthritis: Somatic Mutations In Mature T-Cells Unearthed

Somatic mutations identified in mature cytotoxic CD8+ve T-cells clones in rheumatoid arthritis could be involved in its pathogenesis. Read More

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