Drugs That Reduce Gastric Acid Secretion Can Cause Liver Disease

Proton pump inhibitor (PPI) drugs which block stomach acid secretions and relieve symptoms of frequent heartburn, acid reflux and gastroesophageal reflux disease increases risk of liver disease. The evidence was discovered by the research team at the University of California San Diego School of Medicine. It was found that gastric acid suppression alters specific gut bacteria in a way that promotes liver injury and progression of three types of chronic liver disease in mice as well as humans.
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