Mucopolysaccharidoses (MPS) is a family of rare genetic disorders that affects the central nervous system (CNS). There has been limited research on the disease due to lack of objective measures. In the United States 1 in 25,000 births results in some form of MPS. Life expectancy varies significantly for people with MPS, but individuals with the most severe form rarely live more than 10 years. A research team in the Perelman School of Medicine at the University of Pennsylvania have identified a biomarker associated with MPS. The marker may help in the diagnosis and identification of new drugs for clinical trials for the disease.

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