Protective Effect of Testosterone in Multiple Sclerosis

Multiple sclerosis affects females around three-to-four times more commonly as compared with males. It also manifests at an earlier age in females as compared to males. The male hormone testosterone stimulates the release of a molecule called interleukin 33 (IL-33), which could protect women from multiple sclerosis. The study in mice which revealed this finding was published in the Proceedings of the National Academy of Sciences.