How Metabolic Changes Can Cause Heart Failure

Fatty acids are the major source of energy for the heart and if a metabolic shift to other energy sources takes place, this can result in congestive heart failure. Scientists from the German Cancer Research Center (DKFZ) and Heidelberg University Hospital have now discovered the role of metabolism in heart failure. In addition, these findings are relevant for the use of certain anticancer drugs.

heart failure can also occur due to metabolic changes
- fatty acids are the main fuel source for the heart
- when glucose replaces fatty acids, it causes heart failure
- defect in a signaling molecule Notch-1 is linked to heart failure

Defect in Fatty Acid Signaling Molecule Can Cause Heart Failure

A shift in the metabolism of fatty acids as the energy source to carbohydrates causes congestive heart failure. Read More

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