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New Role of Apolipoprotein E4 Variant in Alzheimers Disease

The presence of ApoE4 increases the brain damage caused by toxic tangles of a different Alzheimer''s-associated protein named tau, concluded a study led by researchers at Washington University School of Medicine in St. Louis. Tau tangles do very little harm to brain cells when ApoE is not present.

ApoE4 variant and Tau proteins in Alzheimer''s Disease (AD) - ApoE4 gene is a high-risk Alzheimer''s Disease gene - Tau protein causes neurofibrillary tangles in AD patients - ApoE4 increases brain damage caused by tau making it a therapeutic target

New Role of Apolipoprotein E4 Variant in Alzheimers Disease

The apolipoprotein ApoE4 is a high-risk Alzheimer's gene that increases brain damage caused by another protein called Tau in Alzheimer's disease patients. Read More

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