Vitamin E to Prevent Acute Kidney Injury in Hospitalized Patients

Vitamin E may reduce the risk of acute kidney injury, a common adverse effect that associates with coronary angiography and percutaneous coronary interventions. Contrast medium-induced acute kidney injury (CIAKI) is the third most frequent cause of hospital-acquired acute kidney injury due to radiological procedures. CM is cleared entirely by the kidney, with a half-life of a few hours. It follows that the dose of CM (volume or gram of iodine) and the half-life [increased with decreased glomerular function rate (GFR)] will determine the net exposure.