Alzheimer's disease actually begins long before the symptoms become clinically apparent. The preclinical phase of increased amyloid levels is the earliest warning sign of Alzheimer's disease, and is considered the incubation period for the disease. Interestingly, this phase often lasts longer than the clinical phase of symptomatic AD. Therapy for Alzheimer's disease should begin during the earliest stage of the disease or the stage of elevated amyloid levels, in order to be effective.
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