Shingles is a condition that causes a painful skin rash with blisters. It appears along a nerve due to reactivation of varicella zoster infection. Acyclovir, a nucleoside analogue, is the first successful antiviral medication, and works well against most species in the herpesvirus family. It is effective against viral infections that include herpes simplex virus (HSV1 and HSV2) infections, chickenpox, and shingles.
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