REYKJAVIK, Iceland, May 31, 2018 /PRNewswire/ --
In a study published today, scientists at deCODE genetics reportnew findings about the founding of the Icelandic population and its subsequent evolution, based on ancient DNA. The study appears today in the online edition of Science.
Iceland was settled around
A striking finding of the study is that, as a result of genetic drift, contemporary Icelanders have diverged from their ancestors in Scandinavia and the British and Irish Isles, while the Viking age settlers are effectively indistinguishable from modern representatives of these source populations. Finally, the new study reports the first discovery of an individual with Klinefelter syndrome based on ancient DNA.
"The mixing of populations and the colonization of new lands are recurring themes in the spread of humans across the globe during the last 70 thousand years," said Agnar Helgason, an author of the paper. "Our study of DNA from the teeth of Viking age Icelanders provides the first in-depth investigation of how a new population is formed through admixture."
"Repeated famines and epidemics led to a substantial loss of sequence diversity from the Icelandic gene pool, causing it to drift away from its source populations in Scandinavia and the British-Irish Isles," said Kári Stefánsson, CEO of deCODE and an author on the paper. "This is a fascinating example of how a population is shaped by its environment, in this case the harsh and marginal conditions of medieval Iceland. It is also another demonstration of how our small but well characterized population can continue to make important contributions to understanding the fundamental genetic and evolutionary processes that shape our species."
Based in Reykjavik, Iceland, deCODE is a global leader in analyzing and understanding the human genome. Using its unique expertise and population resources, deCODE has discovered genetic risk factors for dozens of common diseases. The purpose of understanding the genetics of disease is to use that information to create new means of diagnosing, treating and preventing disease. deCODE is a wholly-owned subsidiary of Amgen (NASDAQ: AMGN).
SOURCE deCODE genetics
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