SEOUL, South Korea, Dec. 3, 2018 /PRNewswire/ -- Kimchi can assist in alleviating symptoms of
The scientific basis supporting this assumption came fromáProfessor Yeong Ok Song's team in the Department of Food Science and Nutrition, Pusan National University, which is one of the research teamsáat World Institute of Kimchi in Korea. The researchárevealed througháexperiments that kimchi and bioactive compounds have positive effects on improving cognitive and memory functions impaired by amyloid beta, cause of Alzheimer's disease. This research finding (Bioactive Compounds in Kimchi Improve the Cognitive and Memory Functions Impaired by Amyloid Beta) was published in the recent issue of "Nutrients" (Oct. 20, 2018).
Professor Song's team intentionally injected amyloid beta into the brains of mice in order to induce Alzheimer's disease. In addition, capsaicin (propionic acid), quercetin (antioxidant component), ascorbic acid (vitamin C), and kimchi extracts were each given to seven mice for two weeks.
Behavioral task tests, such as maze testing, were performed on all mice receiving beta amyloid, and it revealed that learning and memory functions were significantly reduced. However, the degree of a decrease in cognitive function was lower for mice fed with kimchi and its bioactive compounds.
In kimchi-fed mice, the amount of reactive oxygen (the primary cause of aging) generated was lower, and glutathione, a higher quantity of antioxidant enzyme, was produced.
Inflammation of the cerebral nerve from continuous oxidative stress in the brain is also one of the causes of Alzheimer's disease. Inflammatory cytokines (proteins involved in inflammation induction) is largely increased in the brain of patients with Alzheimer's disease. Therefore, non-steroidal anti-inflammatory analgesics are perceived to reduce the risks of Alzheimer's disease. This study also revealed that kimchi and its bioactive compounds significantly reduced the level of inflammatory cytokines. In addition, oxidative stress reduced significantly in mice supplemented with propionic acid and quercetin.
Professor Song said, "It is presumed that the bioactive compounds abundant in kimchi alleviate the symptoms of Alzheimer's disease because of their antioxidant and anti-cancer effects."
About World Institute of Kimchi
A government-funded research institute established to perform research and development related to kimchi, to lead national technological innovation, nature and develop the kimchi industry that will boost the national growth. It performs overall research and development related to kimchi, in order to lead national technological innovation and nurture and develop the kimchi industry that will boost the national growth.
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SOURCE World Institute of Kimchi
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