VK2809 10 mg QOD (n=13) | VK2809 10 mg QD (n=11) | VK2809 combined (n=24) | Placebo (n=11) | |
Median relative % change in liver fat by MRI-PDFF | -56.5% (p=0.0014) | -59.7% (p=0.0003) | -58.1% (p=0.0002) | -8.9% |
Mean absolute % change in liver fat by MRI-PDFF | -8.9% (p=0.011) | -10.6% (p=0.0025) | -9.7% (p=0.0019) | -0.9% |
Percentage of patients experiencing ? 30% reduction in liver fat | 76.9% (p=0.012) | 90.9% (p=0.0019) | 83.3% (p=0.0011) | 18.2% |
Percentage of patients experiencing ? 50% reduction in liver fat | 61.5% (p=0.047) | 72.7% (p=0.03) | 66.7% (p=0.023) | 18.2% |