RedShiftBio Shipping AQS3pro as Industry Endorsements Expand

Wednesday, April 3, 2019 General News
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One year on from introducing the AQS3™pro, a powerful new protein characterization platform, RedShift™ BioAnalytics, Inc. (RedShiftBio) is demonstrating compelling new application data and significant endorsements from leading biopharmaceutical companies.

BURLINGTON, Mass., April 3, 2019 /PRNewswire-PRWeb/ -- The latest application results will be presented at PEGS Boston

2019 and HOS 2019. Driven by industry-leading AQS3delta analytical software, the AQS3pro is transforming the utility of IR spectroscopy for the analysis of protein structure, delivering high sensitivity results in substantially streamlined workflows. With the structure of therapeutic proteins essential to their efficacy and safety, accurate and repeatable measurements are essential from the earliest stages of drug development to commercial manufacture.

"More than 15 major pharmaceutical companies participated in the initial testing of this product, and they provided very clear feedback on its value to the scientist and in drug development," said Chip Marshall, CEO, RedShiftBio. "The AQS3pro being shipped today has greatly benefited from this industry cooperation. Feedback from customers continues to be great."

Proteins are labile, with higher order structure highly sensitive to thermal, chemical and other stresses. The AQS3pro allows users to 'see change' in the secondary structure of proteins across a wide concentration range from 0.1 to over 200 mg/mL, and in the presence of excipients. This makes the AQS3pro uniquely valuable across the biopharmaceutical pipeline, for comparability, stability and aggregation studies, and for formulation screening. Samples can be measured with minimal preparation and without dilution to generate data that is reliably representative of drug performance.

"The level of automation is also a critical feature," said Mr. Marshall. "By enabling simple walkaway operation, the AQS3pro is creating entirely new workflows for protein characterization. It allows scientists to work more efficiently, in ways that are simply impossible with conventional FTIR and many other older tools and techniques with far narrower measurement ranges."

The AQS3pro uses RedShiftBio's Microfluidic Modulation Spectroscopy (MMS) technology, which combines mid-infrared laser spectroscopy with microfluidics and advanced signal processing to provide an order of magnitude in performance. The AQS3delta analytical software automates processing of the resulting data, presenting it in a format that elucidates protein behavior and streamlines information flow for the protein scientist.

Experts from RedShiftBio will be presenting at both HOS 2019 April 8th – 10th San Mateo, CA) and PEGS 2019 (booth #307, April 8th – 12th Boston, MA), and datasets will also be on display in the poster sessions. A sample highlight at both events will be work recently carried out with Celldex Therapeutics Fall River, Massachusetts to analyze a monoclonal antibody from low to high concentration and in different buffers. Results clearly demonstrate the flexibility, high sensitivity and accuracy of AQS3pro and its superiority in protein characterization. To learn more about the system or to register for an event go to


RedShiftBio is a provider of innovative analytical instrumentation for the research, development and manufacture of protein therapeutic drugs. The company has developed the AQS3pro featuring a powerful new analytical technique, Microfluidic Modulation Spectroscopy, or MMS, that enables direct probing of the biophysical structure of proteins. The patented MMS technology provides the comprehensive structural information across five key measurements, in a single automated analysis, replacing the requirement to run samples on multiple instruments. For further information, please visit or email info (at) redshiftbio (dot) com.


SOURCE RedShiftBio

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