MALVERN, Pa., Feb. 15, 2018 /PRNewswire/ -- Realm Therapeutics plc (AIM:RLM), a clinical stage biopharmaceutical company
"In 2017, we set and met transformational goals, turning Realm into a clinical stage company focused on novel therapeutics for immune-mediated diseases," said Alex Martin, Chief Executive Officer of Realm.
"The Company submitted INDs for our two lead candidates, PR022 for Atopic Dermatitis and PR013 for Allergic Conjunctivitis, which the FDA allowed to proceed directly into Phase 2 studies, and both trials were initiated in the fourth quarter of 2017. We are pleased to be ahead of schedule in our PR013 study, with top-line results expected by the end of the first quarter and we are on schedule to release top-line PR022 study results by the end of the third quarter. We are also delighted to confirm our progress in our Acne program as we plan to submit an IND in the fourth quarter and initiate a clinical study shortly thereafter. With current resources and on current plans, Realm is well-positioned to execute on these clinical programs and to explore other potential disease applications for our proprietary immunomodulatory technology through pre-clinical studies."
Clinical Development Highlights
1Eczema Area and Severity Index (EASI) is an investigator-assessed tool used to measure the extent (area) and severity of atopic eczema.2 Investigator Global Assessment (IGA), is an investigator-assessed instrument measuring severity of atopic dermatitis on a 5 grade scale.
About Realm Therapeutics
Realm Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel therapeutics that target the intersection between innate and adaptive immunity, to influence immune signaling and to change the course of immune-mediated diseases in adults and children. Realm's lead drug development programs utilize the Company's proprietary immunomodulatory technology for the treatment of Allergic Conjunctivitis (PR013) and Atopic Dermatitis (PR022) and Realm is exploring its efficacy in Acne and additional Dermatology and Ophthalmology indications as well as other disease areas. For more information on Realm Therapeutics, please visit www.realmtx.com.
Forward Looking Statements
Certain statements made in this announcement are forward-looking statements. These forward-looking statements are not historical facts but rather are based on the Company's current expectations, estimates, and projections about its industry; its beliefs; and assumptions. Words such as 'anticipates,' 'expects,' 'intends,' 'plans,' 'believes,' 'seeks,' 'estimates,' and similar expressions are intended to identify forward-looking statements. These statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties, and other factors, some of which are beyond the Company's control, are difficult to predict, and could cause actual results to differ materially from those expressed or forecasted in the forward-looking statements. The Company cautions shareholders and prospective shareholders not to place undue reliance on these forward-looking statements, which reflect the view of the Company only as of the date of this announcement. The forward-looking statements made in this announcement relate only to events as of the date on which the statements are made. The Company will not undertake any obligation to release publicly any revisions or updates to these forward-looking statements to reflect events, circumstances, or unanticipated events occurring after the date of this announcement except as required by law or by any appropriate regulatory authority.
Contact: Realm Therapeutics plcAlex Martin, Chief Executive OfficerMarella Thorell, Chief Financial Officer and Chief Operating Officer Outside US: +44 (0) 20 3727 1000 US: +1 212 600 1902
Argot PartnersStephanie Marks+1 212 600 1902
FTI ConsultingSimon Conway / Mo Noonan +44 (0) 20 3727 1000
N+1 Singer (Nominated Adviser and Broker) Aubrey Powell / Jen Boorer +44 (0) 20 7496 3000
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SOURCE Realm Therapeutics
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