SUNNYVALE, Calif., Feb. 20, 2018 /PRNewswire/ -- Newly released IDSA/SHEA Clinical Practice Guidelines for C. difficile,
As a partner in reducing rates of C. difficile infection (CDI) worldwide, Cepheid is committed to advancing the use of best practices for detecting and managing CDI, including use of appropriate testing criteria and methodology. To further highlight the discussion surrounding appropriate C. difficile diagnosis and infection prevention, Cepheid recently launched the website www.knowyourpoo.com.
"As the guidelines emphasize, clinical patient evaluation is critical to appropriately diagnosing CDI," said Dr. Niaz Banaei, Director of Clinical Microbiology at Stanford Medical Center. "To reduce over-testing at Stanford, we now require these clinical evaluations be performed upfront before samples are accepted for testing. Once we know that a patient has signs and symptoms consistent with CDI, we want to test them with the most sensitive test available. This approach has improved the overall accuracy of our diagnoses, significantly reduced our CDI rates, and is consistent with the new guidelines."
While the new guidelines mention several approaches for diagnosing CDI, including those that utilize multi-test algorithms, PCR remains the most sensitive method for detecting toxigenic C. difficile, which is critical for both accurate diagnosis and infection prevention activities in hospitals.
"Published studies1 from both Europe and the United States show that antibody-based testing methods, like those used in many algorithmic approaches, are less sensitive than PCR methods, which will lead to missing true cases of CDI. Missed cases, in turn, can lead to spread of infection in hospitals due to under-treatment," said Dr. Fred C. Tenover, Vice President of Scientific Affairs at Cepheid. "PCR's high sensitivity means you can rule out CDI with high confidence and avoid overtreatment of negative patients2. When this is coupled with upfront clinical evaluation, PCR testing becomes a powerful tool for controlling the spread of CDI."
To learn more, visit www.knowyourpoo.com.
About 'KnowYourPoo.com'Testing only appropriate patient specimens can have a dramatic impact on an institution's C. difficile rates2, but it takes a team effort to enforce proper testing criteria. KnowYourPoo.com is a new website committed to helping infection control professionals raise awareness and drive compliance at their facilities through creative educational tools and updates on the latest C. diff news and science. We believe when you Know Your Poo, patients win.
About CepheidBased in Sunnyvale, Calif., Cepheid is a leading molecular diagnostics company dedicated to improving healthcare by developing, manufacturing, and marketing accurate yet easy-to-use molecular systems and tests. By automating highly complex and time-consuming manual procedures, the company's solutions deliver a better way for institutions of any size to perform sophisticated molecular testing in virtually any setting. Through a strong foundation in innovation, the company is focusing on those applications where accurate, rapid, and actionable test results are needed most, such as managing infectious diseases and cancer. For more information, visit http://www.cepheid.com.
For Cepheid Media Inquiries:Darwa Petersondarwa.email@example.com
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