NEW YORK, Aug. 28, 2018 /PRNewswire/ -- Neurotrope, Inc. (NASDAQ: NTRP), a clinical-stage biopharmaceutical company developing
The Company has also been selected to present at the prestigious 25th Annual NewsMakers in the Biotech Industry on Friday, September 7th, 8:30am Eastern Time, at the Millennium Broadway Hotel and Conference Center in New York. This presentation will not be available for webcast.
Drs. Charles Ryan, and Daniel Alkon, Neurotrope's CEO and President / CSO, will provide an overview of the Company's business plan and technology during their live presentations and they will also be available to participate in one-on-one meetings throughout the days with investors who are registered to attend the conferences.
Neurotrope is currently conducting a Confirmatory Phase 2 clinical trial using its lead drug Bryostatin-1, in patients with moderate to severe AD. The therapeutic target of Bryostatin-1 is PKC epsilon. Regeneration of new synaptic networks by PKC epsilon's coordination of synaptic growth factors such as BDNF, NGF and IGF is believed to be responsible for the improvement of patients' cognitive function, recently observed in Neurotrope's Exploratory Phase 2 trial for moderate to severe Alzheimer's patients. These improvements in patients Severe Impairment Battery (SIB) scores were observed, even 30 days after completion of all dosing. Activation of PKC epsilon also activates enzymes such as IDE, ECE and neprilysin. The function of those enzymes are known to degrade A Beta oligomers. PKC epsilon activation also inhibits GSK3beta, which inhibits the production of hyperphosphorylated tau. These multi-modal effects caused by PKC epsilon activation are performed through the activation of innate enzymes in the brain, as opposed to the delivery of monoclonal antibodies currently being utilized by most of the sponsors conducting AD clinical trials.
If you are an institutional investor, and would like to attend the Company's presentation, please click on the following link (www.rodmanevents.com) to register for the conference. Once your registration is confirmed, you will be prompted to log into the conference website to request a one-on-one meeting with the Company.
Event: 20th Annual Rodman & Renshaw Global Investment Conference, sponsored by H.C. Wainwright & Co., LLCDate: September 6th, 2018Time: 4:40 – 5:05 PM (Eastern Time)Location: Maisonnette Lower Level; St. Regis New York Hotel
A live webcast of presentation at the Rodman conference will be available on the Company website in the investors and media section under events and presentations. The presentation will also be archived on the Company's website and be available for replay.
Below is a link to the webcast:
Neurotrope is at the forefront of developing a new approach to combating AD and other neurodegenerative diseases. The Company's world-class science offers the potential to realize a paradigm shift to overcome one of today's most challenging clinical problems — finding a way to slow or even prevent the progression of AD.
In addition to the Company's Phase 2 trial of Bryostatin-1 in advanced AD, Neurotrope has also conducted preclinical studies of bryostatin as a potential treatment for Stroke, Traumatic Brain Injury, and Fragile X Syndrome, Niemann-Pick Type C disease and Rett Syndrome—rare genetic diseases for which only symptomatic treatments are currently available. The FDA has granted Orphan Drug Designation to Neurotrope for Bryostatin-1 as a treatment for Fragile X Syndrome. Bryostatin-1 has already undergone testing in more than 1,500 people in cancer studies, thus creating a large safety data base that will further inform clinical trial designs in AD.
Please visit www.neurotrope.com for further information.
Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements. These forward-looking statements include statements regarding the Phase 2 study and further studies, and continued development of use of Bryostatin-1 for Alzheimer's dementia and other cognitive diseases. Such forward-looking statements are subject to risks and uncertainties and other influences, many of which the Company has no control over. These statements are subject to the risk that further analyses of the Phase 2 data may lead to different interpretations of the data than the analyses conducted to date and/or may identify important implications of the Phase 2 data that are not reflected in these statements. Clinical trial data are subject to differing interpretations, and regulatory agencies, medical and scientific experts and others may not share the Company's views of the Phase 2 data. There can be no assurance that the clinical program for Bryostatin-1 will be successful in demonstrating safety and/or efficacy that we will not encounter problems or delays in clinical development, or that Bryostatin-1 will ever receive regulatory approval or be successfully commercialized. Actual results and the timing of certain events and circumstances may differ materially from those described by the forward-looking statements as a result of these risks and uncertainties. Additional factors that may influence or cause actual results to differ materially from expected or desired results may include, without limitation, the Company's inability to obtain adequate financing, the significant length of time associated with drug development and related insufficient cash flows and resulting illiquidity, the Company's patent portfolio, the Company's inability to expand the Company's business, significant government regulation of pharmaceuticals and the healthcare industry, lack of product diversification, availability of the Company's raw materials, existing or increased competition, stock volatility and illiquidity, and the Company's failure to implement the Company's business plans or strategies. These and other factors are identified and described in more detail in the Company's filings with the SEC, including the Company's Annual Report on Form 10-K for the year ended December 31, 2017, and on Form 10-Q for the quarter ended June 30, 2018. The Company does not undertake to update these forward-looking statements.
Contact information:Investors and MediaJeffrey Benison, Director of Corporate CommunicationsNeurotrope, Inc.516.286.6099 (C) or 212.334.8709 (O)
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SOURCE Neurotrope, Inc.
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