Menicon Undertakes With the Novovision Clinic a Paediatric Myopia Control Clinical Trial

Monday, June 23, 2008 General News
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NAGOYA, Japan, June 23 Although previous studies suggestthat orthokeratology contact lens wear slows the axial length growth of theeye in children with progressing myopia, some limitations in the methodologyemployed have been evident. Using a rigorous study design and precise opticalmeasuring instruments, Menicon Co., Ltd. and the Novovision Clinic in Madridare undertaking the Myopia Control with Orthokeratology contact lenses inSpain (MCOS) study to compare the axial length growth between white Europeanmyopic children wearing orthokeratology contact lenses (OK) and distancesingle-vision spectacles (SP) over a 2-year period. In this prospective,single-centre clinical trial, sixty-two subjects 6 to 12 years of age, andwith myopia of -0.75 to -4.00 D and astigmatism < =1.00 D were randomlyallocated wear OK or SP correction. Measurements of axial length (usingpartial coherence interferometry, Zeiss IOLMaster), anterior chamber depth,corneal topography, cycloplegic refraction and visual acuity are beingperformed at 6-month intervals. To date, no subjects have withdrawn from thestudy, no adverse events were evident and no contact lens fittingmodifications were required in the OK group. The MCOS study offers a number ofnotable features: a prospective design; well matched samples and highresolution ocular biometry measures, which collectively should elucidatewhether OK contact lens wear is a feasible method of myopia control.

"The MCOS study aims, using a rigorous study design and precise opticalmeasuring instruments, at elucidating whether orthokeratology lens wear slowsthe axial length growth of the eye in children with progressing myopia. Thisstudy is of special relevance taking into account that the prevalence ofmyopia has increased substantially over recent decades and now is approaching10-25% and 60-80% in industrialized societies of the West and East,respectively," commented Dr. Jacinto Santodomingo, Global ProfessionalRelations Manager for Menicon Co., Ltd.

"We have been fitting orthokeratology lenses in our clinic for severalyears, during which we observed that myopia tended to progress less inchildren wearing orthokeratology lenses compared to children wearing othermodalities of visual correction. We are delighted to participate in thisunique clinical trial, which should prove whether we are correct about ourpreliminary observations," added Mr. Cesar Villa, Director of Optometry atNovovision.

About Menicon:

Menicon Co., Ltd. (, founded by Mr. Kyoichi Tanaka in1951, is Japan's first and largest contact lens manufacturer, and now isrepresented in over 30 countries. Menicon is a manufacturer dedicated to allareas of soft and GP contact lens related businesses including materialdevelopment, lens designing, and manufacturing of contact lenses and caresolutions. Menicon is a world-leader in the development of hyper-Dk GP(Menicon Z) and soft contact lenses (Menicon PremiO).Contact: Toshio Matsushima Global Business Operations Menicon Co., Ltd. Phone: +81-52-937-5021 Fax: +81-52-935-1121 E-mail: URL:

SOURCE Menicon Co., Ltd.

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