NEW YORK, April 26, 2018 /PRNewswire-USNewswire/ -- The Lupus Research Alliance today announced a collaboration betweenits newly formed affiliate, Lupus Therapeutics, and the pharmaceutical company, Bristol-Myers Squibb (BMS), to test a novel investigational drug, BMS-986165, as a potential new therapy for lupus.
The first of its kind to be tested in lupus,
Lupus Therapeutics will work in collaboration with BMS to identify U.S. sites within the Lupus Clinical Investigators Network (LuCIN) that will be included in the global phase 2 study. Recognizing the limited treatments for lupus, LuCIN was organized, managed and is funded by Lupus Therapeutics as an affiliate of the Lupus Research Alliance to address the slow pace of development of new lupus therapies. LuCIN provides a framework to quickly and cost-effectively test potential new therapies, as well as methods to diagnose and monitor response to treatment.
"There remains a desperate need for effective treatments for lupus without the serious side effects common with existing options," noted Albert Roy, Executive Director, Lupus Therapeutics. "BMS-986165 is a very interesting and promising intervention for patients living with lupus. We are very excited to be partnering with BMS on this trial that we hope advances another treatment option for the disease."
John Throup, Development Team Lead, BMS commented, "Early results to date indicate that BMS-986165 may be a promising oral therapy for people with lupus. Lupus Therapeutics has assembled a Network of world class investigators that are well-positioned to help us assess the potential of BMS-986165 in this disease. We are delighted to work with them as part of the phase 2 program to accelerate clinical development of potential therapies for lupus."
Managing lupus is challenging because no two cases are alike and symptoms vary widely. While better treatments and medical care have improved life expectancy, lupus is still not adequately controlled in many people, and the disease often progresses. With limited treatment options, many of which carry risks of debilitating side effects, there is a strong need for more effective therapies that will reduce the use of steroids, decrease the frequency of disease flares, and have a favorable impact on patients' quality of life.
Click here for more information about the trial testing BMS-986165 as a potential treatment for lupus.
About LupusLupus is a chronic, complex autoimmune disease that affects millions of people worldwide. More than 90% of people with lupus are women; lupus most often strikes during the childbearing years of 15 to 44. African Americans, Latin Americans, Asians and Native Americans are two to three times at greater risk than Caucasians. In lupus, the immune system, which is designed to protect against infection, creates antibodies that can attack any part of the body including the kidneys, brain, heart, lungs, blood, skin, and joints.
About the Lupus Research AllianceThe Lupus Research Alliance aims to transform treatment while advancing toward a cure by financing the most innovative lupus research in the world. The organization's stringent peer review grant process fosters diverse scientific talent who are driving discovery toward better diagnostics, improved treatments and ultimately a cure for lupus. Because the Lupus Research Alliance's Board of Directors fund all administrative and fundraising costs, 100% of all donations goes to support lupus research programs.
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SOURCE Lupus Research Alliance
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