SHANGHAI, July 31, 2018 /PRNewswire/ -- Laekna Inc., a biotechnology company headquartered in Shanghai,
The Pten/PI3K/Akt signaling axis is one of the most critical oncogenic pathways driving cancer growth. Inhibiting this axis has been proven to be effective for many cancer patients, and early clinical results for afuresertib and uprosertib are extremely promising. Laekna has mapped out several clear registration paths for NDA approval potentially as the first in class medicine.
In 2017, Laekna struck its first deal with Novartis, acquiring global rights to develop a CYP17 inhibitor (CFG920), an oral androgen inhibitor, to treat prostate cancer. Before the in-licensing, Novartis had reported positive results from a proof-of-concept study of CFG920 in patients with metastatic castration-resistant prostate cancer.
"Novartis is a global leader in oncology drug innovation. This is the second licensing agreement between Laekna and Novartis, adding to the previous licensing of CFG920 less than a year ago", says Dr. Chris Lu, founder and CEO of Laekna. "We have demonstrated to Novartis that Laekna is a valuable collaborator with our strong commitment, experienced team and financing support from the top investment partners."
"We are dedicated to developing these products rapidly through the regulatory process and into commercialization, with the goal of ultimately benefitting patients around the world," added Amy Xie, VP Operations at Laekna.
Established in 2016, Laekna Therapeutics is a clinical-stage oncology company focused on liver disease and cancer and headquartered in Shanghai's Zhangjiang Hi-Tech Park. The company is committed to the research and development of a new generation of small molecule and antibody-targeted drugs. The founders and staff are R&D and management veterans of large, well-known pharmaceutical companies in China and abroad. The company focuses on delivering innovative medicines to address unmet medical needs. Through collaboration with pharmaceutical companies, CROs, and hospitals, Laekna is committed to delivering more effective and safe medicines to benefit patients in China and around world.
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SOURCE Laekna Inc.
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