Health Canada Approves HEMLIBRA® for Hemophilia A Patients with Inhibitors

¹ American Society of Hematology. Hemophilia: From Plasma to Recombinant Factors. Available at: http://www.hematology.org/About/History/50-Years/1524.aspx. Accessed on July 24, 2018.² HEMLIBRA Product Monograph, August 2, 2018.³ Oldenburg J, et al. Emicizumab Prophylaxis in Hemophilia A with Inhibitors. The New England Journal of Medicine, July 13, 2017.⁴ HEMLIBRA Product Monograph, August 2, 2018.⁵ Canadian Hemophilia Society. All About Carriers – A Guide for Carriers of Hemophilia A and B. Available from: www.hemophilia.ca/wp-content/uploads/2018/04/AACFinal.pdf. Accessed on July 23, 2018.⁶ Canadian Hemophilia Society. All About Carriers – A Guide for Carriers of Hemophilia A and B. Available from: www.hemophilia.ca/wp-content/uploads/2018/04/AACFinal.pdf. Accessed on July 23, 2018.⁷ European Haemophilia Consortium. Bleeding Disorders – Inhibitors. Available from: https://www.ehc.eu/bleeding-disorders/inhibitors/. Accessed on July 23, 2018.⁸ HEMLIBRA Product Monograph, August 2, 2018.⁹ HEMLIBRA Product Monograph, August 2, 2018¹⁰ HEMLIBRA Product Monograph, August 2, 2018.¹¹ HEMLIBRA Product Monograph, August 2, 2018.¹² HEMLIBRA Product Monograph, August 2, 2018.¹³ Canadian Hemophilia Society. All About Carriers – A Guide for Carriers of Hemophilia A and B. Available from: www.hemophilia.ca/wp-content/uploads/2018/04/AACFinal.pdf. Accessed on July 23, 2018.¹⁴ WFH. Guidelines for the management of haemophilia. 2012. Available from: http://www1.wfh.org/publications/files/pdf-1472.pdf. Accessed on July 23, 2018.¹⁵ Franchini M, Mannucci PM. Haemophilia A in the third millennium. Blood Rev 2013; 179-84.¹⁶ Franchini M, Mannucci PM. Haemophilia A in the third millennium. Blood Rev 2013; 179-84.¹⁷ Whelan SF, et al. Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of haemophilia A patients. Blood 2013; 121: 1039-48.¹⁸ HEMLIBRA Product Monograph, August 2, 2018.¹⁹ HEMLIBRA Product Monograph, August 2, 2018.²⁰ HEMLIBRA Product Monograph, August 2, 2018.