Caliper Life Sciences Introduces High Throughput RNA Assay to Improve Workflow in Gene Expression Studies

Friday, September 14, 2007 General News
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HOPKINTON, Mass., Sept. 13 Caliper LifeSciences, Inc. (Nasdaq: CALP) today launched a new high throughput RNA assayfor automatically assessing the concentration, integrity and overall qualityof purified RNA samples. The assay, which was expected by the researchcommunity, was launched on schedule and runs in a microfluidic chip format onCaliper's LabChip 90 instrument and has been designed specifically so thatresearchers can conveniently analyze larger numbers of samples rapidly. Thenew assay measures the integrity of purified RNA samples prior to using suchsamples for critical applications such as microarray analysis or quantitativetranscript analysis using real-time PCR. In combination with the LabChip 90instrument and high throughput analysis software, the new HT RNA assayprovides full walk away automation for up to 300 samples per day, resulting insignificant time and cost savings when carrying out high throughput geneexpression studies.

"Gene expression analysis has become a key tool for new targetidentification, lead optimization, and even for toxicological profiling," saidKevin Hrusovsky, President and CEO, Caliper Life Sciences. "The new HT RNAassay, which compliments our existing LC 90 DNA and protein assays, will allowresearchers to produce a larger amount of significantly higher quality geneexpression data. This new product release reflects our strategy of providingtools and services to enable new experimental approaches that can directlyaccelerate the development and advancement of new drug discovery targets aswell as help move candidate compounds from hits to validated leads."

Caliper's high throughput RNA assay allows for a once-a-day setup withwalk up service throughout the day, ensuring ease-of-use for bench scientistsas they complete this critical part of their workload. The assay is extremelytime-efficient and cost-sensitive, automating RNA quality assessment, reducingmanual pipetting and providing sample integrity assessment results in 80seconds per sample. The microfluidic processing also uses only 2ul of sample,which reserves most of the valuable sample for use in processes furtherdownstream.

About Caliper Life Sciences

Caliper Life Sciences is a leading provider of cutting-edge technologiesenabling researchers in the life sciences industry to create life-saving andenhancing medicines and diagnostic tests more quickly and efficiently.Caliper is aggressively innovating new technology to bridge the gap between invitro assays and in vivo results and then translating those results into curesfor human disease. Caliper's portfolio of offerings includes state-of-the-artmicrofluidics, lab automation & liquid handling, optical imaging technologies,and discovery & development outsourcing solutions. For more informationplease visit

Caliper and LabChip are registered trademarks of Caliper Life Sciences,Inc.

SOURCE Caliper Life Sciences, Inc.

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