Biotech Companies Attempting to Save Lives

Monday, October 23, 2017 General News
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LAS VEGAS, October 23, 2017 /PRNewswire/ --

Companies in the

biotechnology arena are in business to save lives. Such audacious goals come with lots of risk in the stock market, but if successful, even more reward. In the biotech industry, companies can spend hundreds of millions of dollars and in the end have
nothing to show for it. Additionally, Biotech relies on scientific research and data, from this research these companies patent their technologies, and products. A few biotechnology companies to compare and contrast include: Endonovo Therapeutics (OTCQB: ENDV), Pulse Biosciences, Inc. (NASDAQ: PLSE), TherapeuticsMD, Inc. (NASDAQ: TXMD), Genocea Biosciences, Inc. (NASDAQ: GNCA), and Exelixis, Inc. (NASDAQ: EXEL).

Endonovo Therapeutics (OTCQB: ENDV) Market Cap: $18.244M, current share price: $.059  

Just last week, ENDV announced the completion of a study evaluating the effectiveness of its lead platform with positive results. After their success in the completed pre-clinical trial, its apparent ENDV is leading the way in biotechnology and electroceuticals. Their lead platform, Immunotronics™, is a non-invasive electroceutical, and the pre-clinical study measured evaluated it against in a well-established preclinical model of heart failure (post-MI remodeling). This model used Immunotronics™ one, two or three times per day and discovered it drastically increased significantly improved cardiac function and reduced ventricular remodeling, including significant improvements in ejection fraction (EF), fractional shortening (FS) and Left Ventricle Developed Pressure (LVDP), as well as Heart-Weight-to-Body-Weight ratio (HW/BW), which is an index for cardiac hypertrophy (enlarged heart). With its recent success, ENDV plans to continue the development of its pipeline of non-invasive electroceuticals. The completion of this study is a milestone for the electroceutical field and places ENDV as a leader in developing non-invasive therapies for patients with life-threatening inflammatory conditions in vital organs and vascular disease.

Pulse Biosciences, Inc. (NASDAQ: PLSE) Market Cap: $399.34M, current share price: $24.44  

Similar to ENDV's bioelectronics platform, PLSE is developing a therapeutic tissue treatment platform based on Nano-Pulse. Late last month, PLSE announced it has entered into a stock purchase agreement with Robert W. Duggan, an accredited investor and experienced life sciences executive. Mr. Duggan is a current shareholder of the Company and the former Chairman and CEO of Pharmacyclics Inc. The private placement is expected to yield gross proceeds of $30,040,000.

TherapeuticsMD, Inc. (NASDAQ: TXMD) Market Cap: $991.236M, current share price: $4.58  

TXMD is an innovative healthcare company focused on developing and commercializing products exclusively for women. Earlier this month, the Company announced its scheduled for a total of nine presentations at the 2017 North American Menopause Society annual meeting, in Philadelphia, Pennsylvania, October 11-14. These presentations are related to TX-004HR which is the company's investigational applicator-free vaginal estradiol softgel capsule. This is in development for the treatment of moderate-to-severe vaginal pain during sexual intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA), due to menopause.

Genocea Biosciences, Inc. (NASDAQ: GNCA) Market Cap: $46.164M, current share price: $1.61  

Like ENDV, GNCA is working toward creating immunotherapies by targeting T Cell antigens. At the end of last month the Company announced a tactical shift to immuno-oncology with a focus on the development of neoantigen cancer vaccines. This includes its lead candidate, GEN-009, for which it expects to file an Investigational New Drug (IND) application by early 2018.

Exelixis, Inc. (NASDAQ: EXEL) Market Cap: $9.37B, current share price: $31.78  

Exelixis, Inc. is a commercially successful, oncology-focused biotechnology company that strives to accelerate the discovery, development and commercialization of new medicines for difficult-to-treat cancers. Following early work in model genetic systems, we established a broad drug discovery and development platform that has served as the foundation for our continued efforts to bring new cancer therapies to patients in need. We discovered our lead compounds, cabozantinib and cobimetinib, and advanced them into clinical development before entering into partnerships with leading biopharmaceutical companies in our efforts to bring them to patients globally. With growing revenues from the three resulting commercialized products - CABOMETYX®, COMETRIQ®, and COTELLIC® - we are reinvesting in our business to maximize the potential of our pipeline, which we intend to supplement with targeted business development activities and internal drug discovery, all to deliver the next generation of Exelixis medicines and help patients recover stronger and live longer.

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