Arix Bioscience plc: Interim Results for the Six Months Ended 30 June 2018

Monday, July 30, 2018 General News
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LONDON, July 30, 2018 /PRNewswire/ --

Arix Bioscience plc ("Arix") (LSE: ARIX) a global healthcare and life science

company supporting medical innovation, today announces its interim results for the period ended 30 June 2018.

Financial highlights  

  • £35.6m net positive revaluation of core portfolio[1]
  • Successful
    £87m fundraise by the Company from new and existing investors
  • £14.4m of investments made into existing portfolio in the period and a further £4.2m in July 2018
  • Gross portfolio value increased by 71% to £121.8m
  • Net Asset Value of £257.6m; an increase of 76%
  • £29.3m profit before tax in the six month period to 30 June 2018

Operational highlights 

  • Nasdaq listing of two Arix companies during the period
  • Strategic agreements signed by the Company with new investors Fosun International and Ipsen
  • Positive clinical development within the Group; 15 clinical trials underway
  • New strategic agreement signed with Fred Hutchinson Cancer Research Center and Evotec AG; further expanding extensive deal sourcing capabilities
  • Seed investing activity commenced alongside an Arix academic partner

Joe Anderson, Chief Executive Officer of Arix Bioscience plc, commented: "It has been another positive six months for Arix, during which we had a number of encouraging developments in our Group Businesses, leading to £35.6 million of net positive revaluations. At the half year we have delivered meaningful growth in net asset value and we are well positioned to deliver further over the full year. We ended the period with a healthy cash balance to support existing and new businesses.

As a listed company we are able to provide institutional and retail investors access to a diverse portfolio of high growth life science companies, led by some of the most ambitious and brightest minds in biotech." 

About Arix Bioscience plc 

Arix Bioscience plc is a global healthcare and life science company supporting medical innovation. Headquartered in London and with an office in New York, Arix Bioscience sources, finances and builds world class healthcare and life science businesses addressing medical innovation at all stages of development. Operations are supported by privileged access to breakthrough academic science and strategic relationships with leading research accelerators and global pharmaceutical companies.

Arix Bioscience plc is listed on the Main Market of the London Stock Exchange. For further information, please visit http://www.arixbioscience.com

-------------------------------------------------- 

1. Core portfolio comprises of 13 companies: Autolus Therapeutics, Artios Pharma, Harpoon Therapeutics, Aura Biosciences, LogicBio, Mitoconix, PreciThera, Iterum Therapeutics, Amplyx, Depixus, Verona Pharma, OptiKira and Atox Bio. 

 

Arix Bioscience plc - half yearly report for the six months ended 30 June 2018 

CEO's Statement 

It has been another positive six months for Arix, a period during which we had a number of encouraging developments in our Group Businesses, leading to £35.6 million of net positive revaluations, primarily driven by the IPO of Autolus. In addition, we closed an £87 million follow-on fundraising, bringing total capital raised to over £250 million since Arix was founded two and a half years ago. We have established Arix as a leading life science venture capital player with significant commercial and operational expertise.

Our key financial objective remains the delivery of significant returns to shareholders over the longer term by growing our Net Asset Value ("NAV"). During the six months ended 30 June 2018, with the financing and the uplift in Group Business valuations, our NAV increased by 76%, from £146.4 million to £257.6 million. With the new cash, we are well placed to accelerate growth in our existing Group Businesses and embrace further new opportunities for the benefit of our shareholders.

Encouraging developments in Arix's Group Businesses 

We have made positive commercial, operational and developmental progress across the portfolio in the six months ended 30 June 2018, at which date Arix Group Businesses were valued at £102.0 million, including £35.6 million of net positive revaluations in the period.

Autolus, a T-cell programming company, conducted an oversubscribed US$150 million IPO on Nasdaq, supported by a wide range of blue chip institutions. At the end of the period Autolus was trading at $26.79 per share, a 58% uplift to its IPO price; giving a market capitalisation of over US$1 billion. Arix led the Series B in 2016 and since then our £20.8 million investment has increased in value over three-fold. Autolus also commenced further clinical trials, with five programmes now underway in six indications. The company is well placed to achieve its ambition of bringing life-changing treatments to cancer patients by reprogramming their own T-cells.

Within the period we also saw Iterum complete a US$80 million IPO on Nasdaq that will support Phase 3 clinical trials in three indications: uncomplicated urinary tract infections, complicated urinary tract infections and complicated intra-abdominal infections. Trials are due to start later this year, with top line data expected by the end of 2019.

We saw evidence of further value creation in other Group Businesses, including positive Phase 2 COPD data from Verona and strong pre-clinical data from Aura and Harpoon. Atox Bio also commenced a Phase 2 clinical trial in Acute Kidney Injury, with data expected to read out alongside Phase 3 NSTI data in 2019.

Well connected with the pharmaceutical industry 

As potential acquirers of Group Businesses, pharmaceutical companies are one of our key customers as they seek to get ever closer to scientific and medical innovation outside of their own laboratories. During 2017, we have benefited from valuable strategic partnerships with two global pharmaceutical companies, UCB Pharma and Takeda, giving us access to deep scientific knowledge, R&D capabilities, market intelligence and commercial due diligence. We added to this early in 2018, and are pleased to have signed strategic agreements with Ipsen, a global specialty driven biopharmaceutical, and Fosun International, a large Chinese group with a global footprint who offer distribution capability across China. We expect to be sharing life science developments, ideas and co-investment opportunities with our new partners. All four of our pharmaceutical partners have committed meaningful resources to the relationship, and invested in the March 2018 financing of Arix.

Rich, renewable pipeline of opportunities underpinned by extensive global network 

Arix sources its rich pipeline of biotech and life science opportunities from an extensive scientific and clinical network to which Arix has privileged access. The Arix team have wide professional networks with leading global venture capital groups, and we have also established privileged relationships with universities and research accelerators throughout Europe and the US. Within the reporting period we further strengthened our reach by signing a new collaboration with Fred Hutchinson Cancer Research Center and Evotec AG. This new strategic collaboration provides us with an excellent platform to identify new opportunities and build companies with validated, novel scientific approaches, focused on therapeutic breakthroughs for patients suffering from cancer and infectious diseases. Since inception, we have reviewed over 1,000 opportunities, sourced from the UK, US, Europe and globally.

Outlook 

We achieved a significant amount of progress during the first half of 2018: raising capital through new and existing shareholders; expanding the team; signing new pharmaceutical partners; supporting existing Group Businesses; and driving significant progression in NAV.

Looking ahead, we continue to see a rich pipeline of new opportunities through our extensive global networks and we will continue to support the development of our existing Group Businesses. Through 2018 we will be sifting the best ideas and digging deep into due diligence to help build and finance more new companies at the cutting edge of life sciences.  

Led by our experienced team, Arix is progressing well on its goals of advancing innovation in medicine for the benefit of patients. As a listed company we are able to provide institutional and retail investors access to a diverse portfolio of high growth life science companies, led by some of the most ambitious and brightest minds in biotech.

Importantly, our permanent capital structure enables us to stay with our companies for longer than our non-listed competitors to maximise their growth potential and exit at the optimum time for our shareholders. This six months has demonstrated that our differentiated model works, with NAV growing in response to positive developments over the reporting period.

The next couple of years will be an important period for Arix as we see a number of Group Businesses start or progress clinical trials. Initial data are expected by a number of these companies within the next 12 months.

It is important that the companies we have backed continue to report positive developments to drive clear uplifts in value and we are working hard to ensure these goals are met through hands-on involvement with all our Group Businesses. We are also looking to bring on new companies, from seed ideas through to clinical stage companies and will announce these in due course.

We believe our approach has the potential to generate significant value for patients and for investors, and we are grateful to our shareholders for supporting us in this mission.

Dr Joe Anderson, PhD 

Chief Executive Officer

Condensed Consolidated Interim Statement of Comprehensive Income 


   
                                                                    Half Year     Half Year
                                                                   to 30 June    to 30 June
                                                                         2018          2017

                                                                  (unaudited)   (unaudited)
                                                           Note       GBP'000       GBP'000

    Change in fair value of investments                     7          34,869         (218)
    Revenue                                                               472           574
    Administrative Expenses                                           (5,425)       (5,355)
    Operating Profit / (Loss)                                          29,916       (4,999)

    Net finance income                                                    276           (6)
    Foreign exchange gains / (losses)                                     682          (43)
    Share-based payment charge                              10        (1,564)       (1,761)
    Profit / (Loss) before taxation                                    29,310       (6,809)

    Taxation                                                8         (3,636)           126
    Profit / (loss) for the period                                     25,674       (6,683)

    Other Comprehensive Income
    Exchange differences on translating foreign operations                602         (446)
    Taxation                                                8           (113)             -
    Total comprehensive income / (loss) for the period                 26,163       (7,129)

    Attributable to
    Owners of Arix Bioscience plc                                      26,163       (7,129)

    Earnings per share
    Basic earnings per share (GBP)                          6            0.24        (0.10)
    Diluted earnings per share (GBP)                        6            0.22        (0.10)

The above condensed consolidated interim statement of comprehensive income should be read in conjunction with the accompanying notes. 

Condensed Consolidated Interim Statement of Financial Position 


   
                                                               31 December
                                              30 June 2018            2017

                                               (unaudited)       (audited)
                                     Note          GBP'000         GBP'000
    ASSETS
    Non-Current Assets
    Investments held at fair value     7           121,781          71,331
    Intangible assets                                1,913           2,057
    Property, plant and equipment                      420             523
                                                   124,114          73,911

    Current Assets
    Cash and cash equivalents                       97,157          74,938
    Cash on long-term deposit                       40,000               -
    Trade and other receivables                      1,983           1,266
                                                   139,140          76,204

    TOTAL ASSETS                                   263,254         150,115

    LIABILITIES
    Current liabilities
    Trade and other payables                       (1,873)         (3,670)
                                                   (1,873)         (3,670)

    Non-Current Liabilities
    Deferred tax liability             8           (3,749)               -
                                                   (3,749)         (3,670)

    TOTAL LIABILITIES                              (5,622)         (3,670)

    NET ASSETS                                     257,632         146,445

    EQUITY
    Share capital and share premium    9           188,585         105,125
    Retained earnings                               69,261          42,088
    Other reserves                                   (214)           (768)
                                                   257,632         146,445

    TOTAL EQUITY                                   257,632         146,445

The above Condensed Consolidated Interim Statement of Financial Position should be read in conjunction with the accompanying notes.  

Condensed Consolidated Interim Statement of Changes in Equity 

For the six months ended 30 June 2018


   
                                                                Share   Share Translation Retained
                                                              Capital Premium     Reserve Earnings   Total
                                                              GBP'000 GBP'000     GBP'000  GBP'000 GBP'000
    As at 31 December 2017                                         51 105,074       (768)   42,088 146,445
    Profit for the period                                           -       -           -   25,674  25,674
    Other comprehensive income                                      -       -         554     (65)     489
    Contributions of equity, net of transaction costs and tax       -  83,460           -        -  83,460
    Share-based payment charge                                      -       -           -    1,564   1,564
    As at 30 June 2018 (unaudited)                                 51 188,534       (214)   69,261 257,632

   
                                                                Share   Share Translation Retained
                                                              Capital Premium     Reserve Earnings   Total
                                                              GBP'000 GBP'000     GBP'000  GBP'000 GBP'000
    As at 31 December 2016                                         51       -         434   45,844  46,329
    Loss for the period                                             -       -           -  (6,683) (6,683)
    Other comprehensive income                                      -       -       (462)       16   (446)
    Contributions of equity, net of transaction costs and tax       - 105,187           -        - 105,187
    Share-based payment charge                                      -       -           -    1,761   1,761
    As at 30 June 2017 (unaudited)                                 51 105,187        (28)   40,938 146,148

The above Condensed Consolidated Interim Statement of Changes in Equity should be read in conjunction with the accompanying notes.  

Condensed Consolidated Interim Statement of Cash Flows 

For the six months ended 30 June 2018


   
                                                            Half Year to    Half Year to
                                                            30 June 2018    30 June 2017

                                                             (unaudited)     (unaudited)
                                                                 GBP'000         GBP'000
    Cash from operating activities                               (7,215)         (6,471)
    Taxation paid                                                   (28)            (33)
    Net finance income received / (paid)                             275             (6)
    Net cash from operating activities                           (6,968)         (6,510)

    Cash flows from investing activities
    Purchase of equity investments                              (14,320)        (19,455)
    Purchase of property, plant and equipment                        (4)             (1)
    Cash placed on long-term deposit                            (40,000)               -
    Net cash from investing activities                          (54,324)        (19,456)

    Cash flows from financing activities
    Net proceeds from issue of shares                             83,460         105,187
    Net cash from financing activities                            83,460         105,187

    Net increase in cash and cash equivalents                     22,168          79,221

    Cash and cash equivalents at start of period                  74,938          28,929
    Effect of exchange rate changes                                   51               -
    Cash and cash equivalents at end of period                    97,157         108,150

The above Condensed Consolidated Interim Statement of Cash Flows should be read in conjunction with the accompanying notes.  

Notes to the Financial Statements 

1. General information 

The principal activity of Arix Bioscience plc (the "Company") and together with its subsidiaries (the "Arix Group" or "the Group") is to source, finance and develop healthcare and life science businesses globally.

The Company is a public limited company, which is listed on the London Stock Exchange and incorporated and domiciled in the United Kingdom.  The address of its registered office is 20 Berkeley Square, London, WIJ 6EQ.  The registered number is 09777975.

These condensed consolidated interim financial statements were approved for issue on 30 July 2018.

These condensed consolidated interim financial statements do not comprise statutory accounts within the meaning of section 434 of the Companies Act 2006.  Statutory accounts for the year ended 31 December 2017 were approved by the board of directors on 23 April 2018 and delivered to the Registrar of Companies.  The report of the auditors on those accounts was unqualified, did not contain an emphasis of matter paragraph and did not contain any statement under section 498 of the Companies Act 2006.

These condensed consolidated interim financial statements have been reviewed, not audited.

2.Accounting policies  

These condensed interim financial statements for the six months ended 30 June 2018 have been prepared on a going concern basis, in accordance with the Disclosure Guidance and Transparency Rules of the Financial Conduct Authority and with IAS 34, 'Interim financial reporting', as adopted by the European Union. The condensed consolidated interim financial statements should be read in conjunction with the annual financial statements for the year ended 31 December 2017, which have been prepared in accordance with IFRSs as adopted by the European Union.

The accounting policies adopted are consistent with those of the previous financial year.  A number of amendments to IFRSs became effective for the financial year beginning on 1 January 2018, as listed below:

  • Amendments to IFRS 2 'Share-based payments'
  • IFRS 9 'Financial Instruments;
  • IFRS 15 'Revenue from Contracts with Customers'
  • IFRIC 22 'Foreign Currency Transactions and Advance Consideration'
  • Annual Improvements 2014-2016

For the reasons set out on page 82 of the Group's Annual Report and Accounts 2017, the adoption of these new standards and amendments to IFRS did not materially impact the condensed consolidated interim financial statements for the six months ended 30 June 2018 and no retrospective adjustments were made.

Taxes on income in the interim periods are accrued using the tax rate that would be applicable to the expected total annual profit or loss.

3. Estimates 

The preparation of interim financial statements requires management to make judgements, estimates and assumptions that affect the application of accounting policies and the reported amounts of assets and liabilities, income and expense. Actual results may differ from these estimates.

In preparing these condensed consolidated interim financial statements, the significant judgements and estimates made by management in applying the Group's accounting policies and the key sources of estimation uncertainty were the same as those that are set on page 80 of the consolidated financial statements for the year ended 31 December 2017 and no retrospective adjustments were made.

4. Segmental Information 

Information for the purposes of resource allocation and assessment of performance is reported to the Arix Group's Chief Executive Officer, who is considered to be the chief operating decision maker, based wholly on the overall activities of the Arix Group.  It has therefore been determined that the Arix Group has only one reportable segment under IFRS 8 ('Operating Segments'), which is that of sourcing, financing and developing healthcare and life science businesses globally.  The Arix Group's revenue, results and assets for this one reportable segment can be determined by reference to the Consolidated Statement of Comprehensive Income and Consolidated Statement of Financial Position.

Notes to the Financial Statements (continued) 

5. Financial Risk Management and Financial Instruments 

The Arix Group's activities expose it to a variety of financial risks: market risk (including currency risk, fair value interest rate risk, and cash flow interest rate risk), credit risk and liquidity risk.

The condensed consolidated interim financial statements do not include all financial risk management information and disclosures required in the annual financial statements; they should be read in conjunction with the Group's annual financial statements as at 31 December 2017.  There have been no changes in the risk management department or in any risk management policies since the year end.

6. Earnings per Share 

Basic earnings per share is calculated by dividing the profit/(loss) attributable to equity holders of Arix Bioscience plc by the weighted average number of unrestricted shares.

Potentially dilutive ordinary shares include options and conditional share awards issued under the Company's long term incentive plans.


   
                                                                                 2018         2017
                                                                              GBP'000      GBP'000
    Profit/(loss) attributable to equity holders of Arix Bioscience plc        26,163      (7,129)
    Weighted average number of shares in issue                            110,060,821   70,957,612
    Fully diluted weighted average number of shares                       118,805,702          N/A
    Basic earnings/(loss) per share                                           GBP0.24    (GBP0.10)
    Diluted earnings/(loss) per share                                         GBP0.22    (GBP0.10)

 

7. Investments 


   
                                              Level 1-       Level 3 -
                                                Quoted        Unquoted
                                           Investments     Investments       Total
                                               GBP'000         GBP'000     GBP'000
    At 31 December 2017                          2,846          68,485      71,331
    Additions                                    8,769           5,551      14,320
    Transfers                                   29,620        (29,620)           -
    Unrealised gain on investments              34,183             686      34,869
    Foreign exchange gains                         659             602       1,261
    At 30 June 2018                             76,077          45,704     121,781

Transfers from Level 3 to Level 1 reflects companies which have listed during the period.  Level 3 investments are valued with reference to either price of recent investment (£36.2m); a Monte Carlo simulation (£0.1m); net asset value (£5.6m); or by discounted cash flow (£3.8m); the latter used a discount rate of 23%, a discount for marketability (20%) and other assumptions relating to exit values and exit dates; these assumptions are unchanged from those disclosed at 31 December 2017.  The sensitivity of the discounted cash flow valuation was considered; a 25% reduction in the exit assumptions of the underlying assets would result in the £3.8m valuation being reduced to £0.7m.

Notes to the Financial Statements (continued) 

 

7. Investments (continued) 


   
                                                      Level 1-      Level 3 -
                                                        Quoted       Unquoted
                                                   Investments    Investments      Total
                                                       GBP'000        GBP'000    GBP'000
    At 31 December 2016                                  2,020         15,095     17,115
    Additions                                            1,780         17,675     19,455
    Unrealised (loss) / gain on investments              (789)            571      (218)
    Foreign exchange losses                               (13)          (456)      (469)
    At 30 June 2017                                      2,998         32,885     35,883

As permitted by IAS 28 'Investment in Associates' and in accordance with the Arix Group accounting policy, investments are held at fair value even though the Arix Group may have significant influence over the companies.  Significant influence is determined to exist when the Group holds more than 20% of the holding or when less than 20% is held but in combination with a certain level of board representation is deemed to be able to exert significant influence.  As at 30 June 2018, the Arix Group is deemed to have significant influence over the following entities:


   
                                 Net Assets /     Profit /
                     % of Issued (Liabilities    (Loss) of
                           Share ) of Company      Company
            Company Capital Held      GBP'000      GBP'000   Date of Financial Information
    Depixus SAS            18.6%          N/A          N/A Accounts not publicly disclosed
    OptiKira, LLC          26.0%          N/A          N/A Accounts not publicly disclosed
    PreciThera, Inc        17.8%          N/A          N/A Accounts not publicly disclosed

Notes to the Financial Statements (continued) 

 

7. Investments (continued) 


   
                                                                                             Fully
                                                                                             Dilut
                                                                                                ed
                                                                                             Equit
                                                              Net Change       Fully             y
                                                          31 Inve     in       Dilut Funding Inter
                                                        Dece stme Valuat          ed Committ   est
                                                        mber   nt    ion    30 Equit ed, Not  When
                                                        2017   in (inclu  June     y     Yet Fully
                                                        Valu Peri   ding  2018 Inter Investe Commi
                                                           e   od    FX) Value   est       d  tted
                                                        GBPm GBPm   GBPm  GBPm     %    GBPm     %
    Amplyx Pharmaceuticals                               2.8    -      -   2.8  2.8%     1.8  3.8%
    Artios Pharma                                        3.7    -      -   3.7 14.7%     1.4 14.9%
    Atox Bio                                             3.0    -    0.1   3.1  3.7%     3.0  6.4%
    Aura Biosciences                                     2.5    -      -   2.5  5.3%     1.2  6.6%
    Autolus Therapeutics                                20.1  5.5   38.6  64.2  7.9%       -  7.9%
    Depixus                                              1.1  0.3 -        1.4 18.6%     0.1 19.2%
    Harpoon Therapeutics                                 5.1    -    0.1   5.2  8.0%     4.2 12.3%
    Iterum Therapeutics                                  5.7  6.7  (4.1)   8.3  7.4%       -  7.4%
    LogicBio Therapeutics                                4.8    -    0.1   4.9 13.3%     2.7 15.4%
    Mitoconix Bio                                        0.4    -      -   0.4  2.1%     2.7  9.0%
    OptiKira                                             1.3    -      -   1.3 26.0%       - 26.0%
    PreciThera                                           0.5    -      -   0.5 17.8%     5.4 23.4%
    Verona Pharma                                        2.9    -    0.8   3.7  2.5%       -  2.5%
    Group Businesses                                    53.9 12.5   35.6 102.0          22.5

    BioMotiv                                             5.8  1.8    0.7   8.3 17.8%       - 17.8%
    Simbec-Orion Group                                   2.0    -      -   2.0   N/A       -   N/A
    Arthurian Life Sciences Carried Interest Partner LP  3.8    -      -   3.8   N/A       -   N/A
    The Wales Life Sciences Investment Fund LP           5.8    -  (0.2)   5.6   N/A       -   N/A
    Other                                                  -  0.1      -   0.1   N/A       -   N/A
    Other Interests                                     17.4  1.9    0.5  19.8             -

    TOTAL                                               71.3 14.4   36.1 121.8          22.5

Notes to the Financial Statements (continued) 

 

8. Taxation 


   
                                                                  Half Year     Half Year
                                                                 to 30 June    to 30 June
                                                                       2018          2017

                                                                (unaudited)   (unaudited)
                                                                    GBP'000       GBP'000
    Current period tax charge
    Current Tax                                                           -            35
    Deferred tax                                                      3,636         (161)
    Total tax charge/(credit)                                         3,636         (126)

    Statement of Other Comprehensive Income - tax charge
    Current Tax                                                           -             -
    Deferred tax                                                        113             -
    Total tax charge                                                    113             -

    Reconciliation of tax charge
    Profit/(loss) before tax                                         29,310       (6,809)

    Expected tax based on 19.00% (2017: 19.50%)                       5,568       (1,328)

    Effects of:
    Expenses not deductible for tax purposes                             83            34
    Income not taxable                                                   69             -
    Impact of rate between deferred tax and current tax               (640)             4
    Recognition of deferred tax asset previously unrecognised       (1,616)             -
    Deferred tax not recognised                                         172         1,164
    Total tax charge / (credit)                                       3,636         (126)

    Recognised deferred tax provisions
    Brought forward                                                       -           280
    Relating to Profit and Loss                                       3,636         (161)
    Relating to Other Comprehensive Income                              113             -
    Carried forward                                                   3,749         (280)

A reduction in the UK corporation tax rate from 20% to 19% (effective from 1 April 2017), and an additional reduction to 17% (effective 1 April 2020) was substantively enacted on 6 September 2016. This will reduce the company's future current tax charge accordingly. The deferred tax liability at 30 June 2018 has been calculated based on these rates.

Deferred tax assets are recognised to the extent that the realisation of the tax benefit through future taxable profits is probable. The Group did not recognise deferred tax assets of £503k (2017: £1,948k) in respect of losses due to uncertainty over their utilisation.

Notes to the Financial Statements (continued) 

 

9. Share Capital 


   
                                                    As at 30 June     As at 31
                                                             2018     Dec 2017
    Allotted and called up
    Ordinary shares of GBP0.00001 each (#)            134,823,243   96,153,090
    Ordinary shares of GBP0.00001 each (GBP'000)                1            1
    49,671 Series C shares of GBP1 each (GBP'000)              50           50

On 20 March 2018, the Company raised approximately £87 million in a capital raising, from both new and existing investors. A total of 38,610,928 new Ordinary Shares were issued at a price of £2.25 per share.

On 22 June 2018, the Company allotted 45,892 new ordinary shares to non-executive directors, in accordance with the Company's Remuneration Policy and the compensation agreed at their appointments.  A further 13,333 new ordinary shares were allotted relating to an award under the Company's Executive Incentive Plan.

 

10. Share Options 

Executive Share Option Plan 

On 8 February 2016, options were granted pursuant to the Executive Share Option Plan to two directors at an exercise price of £1.80 per ordinary share. The number of ordinary shares subject to the options are the requisite number of ordinary shares as represents 5.43% of the fully diluted ordinary share capital of the Company immediately following the end of the Company's stabilisation period following admission to the London Stock Exchange.  Options with identical terms were offered to the founders of the Company constituting 5.00% of the issued share capital of the Company after admission. As such, the number of options granted for both management and founders was confirmed on 20 March 2017. All conditions are unchanged from those disclosed in the 31 December 2017 financial statements.

Executive Incentive Plan 

On 22 February 2017, nil cost options were granted pursuant to the Executive Incentive Plan to certain directors and members of staff.  The options vest on 22 February 2019 and may be exercised from this date until 21 February 2027. The options are contingent on remaining in employment with a company in the Arix Group, and are subject to malus and clawback provisions.

On 26 May 2017, options were granted pursuant to the Executive Incentive Plan to certain directors and members of staff. The options vest on 26 May 2020, subject to the Company's share value growth over the three-year performance period.  The options are contingent on remaining in employment with a company in the Arix Group, and are subject to malus and clawback provisions.

On 17 May 2018, options were granted pursuant to the Executive Incentive Plan to certain directors and members of staff. The options vest on 17 May 2021, subject to the Company's share value growth over the three-year performance period. The options are contingent on remaining in employment with a company in the Arix Group, and are subject to malus and clawback provisions.

Share based payments 

The fair value of options granted under the Executive Share Option Plan was calculated using the Black-Scholes model.  The assumptions used in this calculation are unchanged from those disclosed in the 31 December 2017 financial statements.

As the 22 February 2017 options have no performance conditions, the share based payment charge is calculated by reference to the Company's share price on the grant date; the charge is recognised over the two-year vesting period.

The charge associated with the 26 May 2017 options have been calculated using a Monte Carlo simulation, incorporating relevant assumptions for share price (197.5p), expected volatility based on similar quoted companies (44%), risk free interest rate (0.12%) and share option term (three years). The resultant fair value is then spread over the three-year relevant vesting period.

Notes to the Financial Statements (continued) 

10. Share Options (continued) 

The charge associated with the 17 May 2018 options have been calculated using a Monte Carlo simulation, incorporating relevant assumptions for share price (209.0p), expected volatility based on similar quoted companies (37%), risk free interest rate (0.93%) and share option term (three years). The resultant fair value is then spread over the three-year relevant vesting period.

For the six months to 30 June 2018, a share based payment charge of £1,564,000 (30 June 2017: £1,761,000) has been recognised for a variety of share based payment schemes offered by the Group.

Charges of £309,000 and £186,000 were recognised in relation to the management options and founder incentive options respectively, granted under the Executive Share Option Plan.  A charge of £729,000 was recognised in relation to the 22 February 2017 Executive Incentive Plan award; £213,000 in relation to the 26 May 2017 award; £97,000 in relation to the 17 May 2018 award; and £30,000 in relation to shares issued to non-executive directors who receive 50% of their fee as shares, in accordance with the Company's Remuneration Policy and the compensation agreed at their appointments.

11. Related Party Transactions 

During the period, consultancy fees amounting to £374,400 (inclusive of VAT) (30 June 2017: £121,000) were payable to Merlin Scientific LLP, a partnership controlled by Sir Christopher Evans, a director and substantial shareholder of the Company. At 30 June 2018, no amount (inclusive of VAT) was owed to Merlin Scientific LLP by the Company in respect of these fees (30 June 2017: £31,000).

During the period, Arix Capital Management Limited, as manager of The Wales Life Sciences Investment Fund LP, recognised management fee income totalling £454,000 (six months to 30 June 2017: £554,000).  Arix Capital Management Limited is also a limited partner of the fund.  As at 30 June 2018, £409,000 was outstanding (30 June 2017: £961,000).

David U'Prichard, a non-executive director of the Company, provides consulting services and administrative support to BioMotiv LLC. The consulting services and administrative support are provided through Druid Consulting LLC, a firm controlled by David U'Prichard. The Company is a stakeholder of BioMotiv LLC.  During the period ended 30 June 2018, Druid Consulting LLC received a total of $209,946 from BioMotiv LLC (30 June 2017: $136,298).

On 28 February 2018, €0.3m (£0.3m) was invested in Depixus SAS, a company which the Arix Group is deemed to have significant influence, in line with existing commitments.

On 9 May 2018, The Wales Life Sciences Investment Fund LP, a fund managed by Arix Capital Management Limited called £6,000 of capital from Arix Capital Management Limited as a limited partner of the fund.

12. Events After the Reporting Period 

On 17 July 2018, a further $5.5m (£4.2m) was invested in Harpoon Therapeutics, Inc. The Arix Group's fully diluted shareholding in the company now stands at 12.3%.

Statement of Directors' Responsibilities 

The Directors confirm that to the best of their knowledge these consolidated condensed interim financial statements have been prepared in accordance with International Accounting Standard 34, 'Interim Financial Reporting', as adopted by the European Union and that the interim management report includes a fair review of the information required by DTR 4.2.7 and DTR 4.2.8, namely:

  • An indication of important events that have occurred during the first six months and their impact on the consolidated condensed interim set of financial statements, and a description of the principal risks and uncertainties for the remaining six months of the financial year; and
  • Material related-party transactions in the first six months and any material changes in the related-party transactions described in the last annual report.

The Directors are responsible for the maintenance and integrity of the Company's website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements may differ from legislation in other jurisdictions.

The directors of Arix Bioscience plc are listed in the company's Annual Report for 31 December 2017, excluding John Hutton, who stepped down from the board on 31 May 2018.

By order of the Board

James Rawlingson

Chief Financial Officer

30 July 2018

Independent review report to Arix Bioscience plc 

Report on the Half-Yearly Report and Condensed Consolidated Interim Financial Statements 

Our conclusion 

We have reviewed Arix Bioscience plc's Half-Yearly Report and Condensed Consolidated Interim Financial Statements (the "interim financial statements") in the half-yearly report and condensed consolidated interim financial statements of Arix Bioscience Plc for the six month period ended 30 June 2018. Based on our review, nothing has come to our attention that causes us to believe that the interim financial statements are not prepared, in all material respects, in accordance with International Accounting Standard 34, 'Interim Financial Reporting', as adopted by the European Union and the Disclosure Guidance and Transparency Rules sourcebook of the United Kingdom's Financial Conduct Authority.

What we have reviewed 

The interim financial statements comprise:

  • the condensed consolidated interim statement of financial position as at 30 June 2018;
  • the condensed consolidated interim statement of comprehensive income for the period then ended;
  • the condensed consolidated interim statement of cash flows for the period then ended;
  • the condensed consolidated interim statement of changes in equity for the period then ended; and
  • the explanatory notes to the condensed interim financial statements.

The interim financial statements included in the half-yearly report and condensed consolidated interim financial statements have been prepared in accordance with International Accounting Standard 34, 'Interim Financial Reporting', as adopted by the European Union and the Disclosure Guidance and Transparency Rules sourcebook of the United Kingdom's Financial Conduct Authority.

As disclosed in note 2 to the interim financial statements, the financial reporting framework that has been applied in the preparation of the full annual financial statements of the Group is applicable law and International Financial Reporting Standards (IFRSs) as adopted by the European Union.

Responsibilities for the interim financial statements and the review 

Our responsibilities and those of the directors 

The half-yearly report and condensed consolidated interim financial statements, including the interim financial statements, is the responsibility of, and has been approved by, the directors. The directors are responsible for preparing the half-yearly report and condensed consolidated interim financial statements in accordance with the Disclosure Guidance and Transparency Rules sourcebook of the United Kingdom's Financial Conduct Authority.

Our responsibility is to express a conclusion on the interim financial statements in the half-yearly report and condensed consolidated interim financial statements based on our review. This report, including the conclusion, has been prepared for and only for the company for the purpose of complying with the Disclosure Guidance and Transparency Rules sourcebook of the United Kingdom's Financial Conduct Authority and for no other purpose. We do not, in giving this conclusion, accept or assume responsibility for any other purpose or to any other person to whom this report is shown or into whose hands it may come save where expressly agreed by our prior consent in writing.

What a review of interim financial statements involves 

We conducted our review in accordance with International Standard on Review Engagements (UK and Ireland) 2410, 'Review of Interim Financial Information Performed by the Independent Auditor of the Entity' issued by the Auditing Practices Board for use in the United Kingdom. A review of interim financial information consists of making enquiries, primarily of persons responsible for financial and accounting matters, and applying analytical and other review procedures.

A review is substantially less in scope than an audit conducted in accordance with International Standards on Auditing (UK) and, consequently, does not enable us to obtain assurance that we would become aware of all significant matters that might be identified in an audit. Accordingly, we do not express an audit opinion.

We have read the other information contained in the half-yearly report and condensed consolidated interim financial statements and considered whether it contains any apparent misstatements or material inconsistencies with the information in the interim financial statements.

PricewaterhouseCoopers LLP Chartered Accountants London 30 July 2018

Enquiries For more information on Arix, please contact: 

 

Arix Bioscience plc Charlotte Parry, Head of Investor Relations +44(0)20-7290-1072 charlotte@arixbioscience.com

Burns McClellan (US Media & IR Enquiries) Lisa Burns, John Grimaldi, Bill Slattery Jr. +1-212-213-0006 arix@burnsmc.com

SOURCE Arix Bioscience plc



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