Altogen Biosystems Launched cGMP-grade Nanoparticle Transfection Reagent for In Vivo Delivery

Thursday, May 31, 2018 General News
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LAS VEGAS, May 31, 2018 /PRNewswire/ -- Altogen Biosystems is a manufacturer of life science research products that includes

in vivo transfection reagents designed for tissue-targeted delivery of biomolecules. Altogen's Nanoparticle In Vivo Transfection Reagent was launched in 2008 and used in over 30 research publications demonstrating highly efficient delivery of cargo
nucleic acids (siRNA, microRNA, mRNA, plasmid DNA, and small proteins) to the heart, lung, liver, pancreas, kidney, and various tumor types. In vivo reagent offers high transfection efficiency, reproducibility, robustness and represent a novel promising approach for medical applications such as gene and oligonucleotides therapy.

Altogen Biosystems offers over 120 cell-line optimized in vitro delivery kits and seven in vivo transfection reagents that are functionally tested in both mice and rats to provide effective intracellular delivery via various administration routes, including intravenous, intraperitoneal, and intratumoral injection. Nanoparticle In Vivo Transfection Reagent was selected as the delivery vehicle of choice in several drug development programs. For this purpose, Altogen Biosystems provides a cGMP grade transfection reagent required for clinical trials.

Altogen Labs, a GLP-compliant preclinical research laboratory, completed preclinical testing of Nanoparticle In Vivo Transfection Reagent. According to Dr.Dmitriy Ovcharenko (Altogen Labs CEO), proprietary formulation of chemically engineered nanoparticles enable protection of cargo biomolecules in vivo and tissue-targeted delivery of therapeutic compounds while not inducing an inflammatory response. This transfection technology can be used as experimental research tools for oncology studies, diabetes, cirrhosis, and many other conditions. Development of novel medicines often depend on successful delivery of therapeutic molecules to the target cells and tissues.

About Altogen Biosystems

Altogen Biosystems is a life sciences company focused on development and manufacture of transfection products. Altogen scientists use combinatorial chemistry and cell and molecular biology to develop advanced transfection technologies. Altogen Labs provides in vivo and in vitro biology CRO laboratory services, including over 100 xenograft models (CDX and PDX) designed to expedite preclinical research, different types of pharm/tox studies, development of stable cell lines, IC50 and ELISA testing, genome-wide siRNA library screening, custom liposome encapsulation, safety, and in vivo toxicology studies.

Altogen Biosystems848 Rainbow Blvd #823Las Vegas, NV, 89107 USAPhone: (702) 349-6103Fax: (702) 989-0841Email: corporate@altogen.com

 

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SOURCE Altogen Biosystems



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