The cardinal signs of leprosy are
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Hypopigmentation
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Anaesthesia or hypoaesthesia
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Nerve thickening
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Presence of acid fast bacillus in the skin smear.
A diagnosis of leprosy can be made if any two of i. _ iii are present or iv is present.
Slit skin
The severity of the disease and the progress during treatment can be assessed by one of two indices.
The bacteriological index is given value as follows:
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6 + Many clumps of bacilli in the average field (over 100)
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5 + 100-1000 bacilli/field
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4 + 10-100 bacilli/field
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3 + 1-10 bacilli/field
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2 + 1-10 bacilli in co-fields
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1 + 1-10 bacilli in co-fields
In the bacteriological index both the viable and the nonviable forms are taken into account. Hence the more sensitive index is the Morphological Index (M.I.) which is expressed as a number being the ratio of solid forms to that of the total Bacillary count.