2. Generalized pustular psoriasis
This is one of the most severe form of Psoriasis. The precipitating factors are intermittent infections, hypocalcemia and sudden withdrawal of systemic steroid usage. This condition may occur during pregnancy (impetigo herpetiformis) and may be associated with fetal and maternal mortality. It is characterized by severe constitutional symptoms.


The pustules appear in crops or waves in psoriatic lesions or in normal skin. Complications encountered are dehydration, hypocalcemia, hypoalbuminemia and septicemia. In addition to the general management of the complications, specific treatment includes systemic steroids, methotrexate, oral retinoids or cyclosporin-A.









Comments

@Albularyo, Canada

Exfoliative dermatitis includes also Seborrhea for which a steroid i.e. Betamethasone Valerate 0.2% is prescribed. However a good scrubbing with bath salts, like skin-friendly Epsom Salt (Magnesium Sulphate) after a shower, will have the same temporary effect, without the nasty side-effects of Steroids. On the scalp Alcohol will prevent excessive dandruff for a day or so.

@drjai23, India

Why this difference between type 1 and type 2 reactions and why there is difference even in treatment also .