Managing Pshyciatric Disorders in Primary Care

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Medications that can Cause Depression

  • Amphetamines
  • Antihypertensives (clonidine, propranolol, thiazides, reserpine)
  • Benzodiazepines
  • Cimetidine
  • Cocaine
  • Hormones
    (oral contraceptives)
  • Interferon
  • Isotretinoin
  • Nonsteroidal anti-inflammatory agents
  • Ranitidine
  • Steroids
Questions should also be directed at the possibility of recreational drug or alcohol
use. Studies suggest that 10% to 30% of alcoholic patients suffer from depression. Ideally, patients who are using mind-altering substances should discontinue them and be reevaluated before antidepressant drug treatment is initiated. In the real world,
this often is impossible, and treatment of depression with a selective serotonin reuptake inhibitor (SSRI) may help promote abstinence from alcohol. Use of tricyclic antidepressants or monoamine oxidase inhibitors should be avoided in this group.

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This was a very helpful article in doing an assignment for Abnormal Psychology at Colorado Technical University in my RN to BSN program. Thank you.

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