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Acid Peptic Disease

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Prof. Ashok Sundarraman, MS, FRCS, FICS*

Peptic ulcers occur in presence of Acid and Pepsin. The two main types are gastric and duodenal but they can also occur at GJ Stoma, lower end of esophagus

and Meckels diverticulum with ectopic gastric mucosa. According to duration and complexity of symptoms they can be acute or chronic.

Acute Peptic Ulcers:

Etiology: Disruption of gastric mucosal barrier appears as multiple erosions. 50% of patients give history of NSAID/aspirin intake and classically they present with hemorrhage.

Pathology: Frequently multiple.

Stomach - They can occur in any part.

Duodenum - Almost always confined to first part.

Shallow punched out and seldom invade musclecoats unlikely to leave scars healing.

Clinical features: Short lived attacks of dyspepsia - not recognized. Haemetemesis - recognized.

Acute duodenal ulcer in anterior wall occasionally perforates. These acute lesions can progress to chronic ulcers.


  • Cause must be removed.

  • Medical management has good response.

  • Blood - transfusions for haemetemesis.

  • Dietetic irregularities to be corrected.


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jungle, Saudi Arabia

I am suffering from acid peptic disease as the doctor told me and I want to try this lemon water drink in empty stomach in early morning before I have my breakfast. Does this drink worsen my disease as I read that lemon inside the body is alkaline not acid. Thank you.

sivakumar99, India

useful information

nikkay_28, Philippines

i am suffering a stomach ache and the doctor told me that i have acid peptic deasease. what kind of food should i take? thank you so much nikki from philippines

LaltuSarkar, N/A

i want to feel 1.5 years suffer burning in my stomuch but it is not right. i check endoscopy. answare is amtal gastritis/duodenal erosions. also biopsy that report is "Mild chronic antral gastritis, negative for H-pylori, gastric antral(endoscopic)biopsy." it is hapend 6 month ago. medicin doctor has been given nekfiune,zentel, nultivite gold. for 2 month but it is not work properly

jforkner_013, United States

hi i've just been diagnosed with acid peptic disease and i was wondering what we can and cannot eat

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