Review the side-effects of Zotepine as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Diarrhea, dyspepsia, constipation, dry mouth
Central Nervous System: Anxiety, depression, agitation, headache, insomnia, fluctuations in body temperature, drowsiness, seizures and hyperprolactinemia
Cardiovascular: Increased heartbeat, decreased blood pressure, heart rhythm abnormalities
Eye: Blurred vision, angle-closure glaucoma (eye disease that results in optic nerve damage or vision loss induced by raised pressure in the eye)
Others: Movement disorders like tardive dyskinesia, neuroleptic malignant syndrome, increased liver function tests, weight gain, sweating, abnormal blood cell counts, weakness
• ECG, electrolytes levels, complete blood cell count and liver function tests have to be monitored at regular intervals.
• Rapid discontinuation of zotepine is not advised as it leads to rebound psychosis and hence the drug requires gradual decreasing of dose.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Diarrhea, dyspepsia, constipation, dry mouth
Central Nervous System: Anxiety, depression, agitation, headache, insomnia, fluctuations in body temperature, drowsiness, seizures and hyperprolactinemia
Cardiovascular: Increased heartbeat, decreased blood pressure, heart rhythm abnormalities
Eye: Blurred vision, angle-closure glaucoma (eye disease that results in optic nerve damage or vision loss induced by raised pressure in the eye)
Others: Movement disorders like tardive dyskinesia, neuroleptic malignant syndrome, increased liver function tests, weight gain, sweating, abnormal blood cell counts, weakness
Other Precautions :
• Elderly patients should monitor blood pressure before starting zotepine treatment and for the first few weeks of treatment.• ECG, electrolytes levels, complete blood cell count and liver function tests have to be monitored at regular intervals.
• Rapid discontinuation of zotepine is not advised as it leads to rebound psychosis and hence the drug requires gradual decreasing of dose.
