Side effect(s) of Trifluridine and Tipiracil

Review the side-effects of Trifluridine and Tipiracil as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Gastrointestinal: Nausea, vomiting, stomach pain, diarrhea, stomatitis, loss of appetite

  Nervous system: Headache, dizziness, taste disturbances, abnormal weakness, peripheral neuropathy, inability to sleep

  Cardiovascular: Abnormal heart rhythm, heart attack, fluctuations in blood pressure

  Respiratory: Chest pain, cough, breathing difficulty, a blood clot in the lungs

  Skin: Rashes, hair loss, dry skin, itching

  Lab abnormalities: Low levels of red blood cells, neutrophils, and platelets, increased levels of liver enzymes, urea, and creatinine

Other Precautions :

There is no specific antidote for trifluridine and tipiracil overdose. So, patients must be treated accordingly for the symptoms and signs of an overdose under medical supervision in a multispeciality hospital.