Review the side-effects of Trametinib as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
General: Swelling of the face, arms, legs and feet, fever, weakness, diarrhea, pain in abdomen.
Skin: Rashes, severe skin reactions, skin infections, nail disease, itching. Skin toxicity may be serious enough to require hospitalization.
Cardiovascular system: High blood pressure, cardiomyopathy (heart muscle related diseases), heart failure.
Central nervous system: Dizziness
Respiratory: Shortness of breath, difficulty in breathing, lung diseases, pneumonitis, cough, nose bleed.
Blood: Anemia, low white blood cell count, bleeding.
Eye: Blurred vision, dry eyes, loss of vision, retinal vein occlusion (blockage of blood supply to the retinal vein).
Liver: Increase in liver enzymes.
Trametinib should be taken on an empty stomach as intake of food may delay the absorption of the drug and reduce its effectiveness.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
General: Swelling of the face, arms, legs and feet, fever, weakness, diarrhea, pain in abdomen.
Skin: Rashes, severe skin reactions, skin infections, nail disease, itching. Skin toxicity may be serious enough to require hospitalization.
Cardiovascular system: High blood pressure, cardiomyopathy (heart muscle related diseases), heart failure.
Central nervous system: Dizziness
Respiratory: Shortness of breath, difficulty in breathing, lung diseases, pneumonitis, cough, nose bleed.
Blood: Anemia, low white blood cell count, bleeding.
Eye: Blurred vision, dry eyes, loss of vision, retinal vein occlusion (blockage of blood supply to the retinal vein).
Liver: Increase in liver enzymes.
Other Precautions :
Do not breast feed your baby while taking trametanib.Trametinib should be taken on an empty stomach as intake of food may delay the absorption of the drug and reduce its effectiveness.