Terizidone- Side effect(s)

Read the side effects of Terizidone as described in the medical literature. In case of any doubt consult your doctor or pharmacist.

Gastrointestinal: Nausea and vomiting

Cardiovascular system: Tremors, congestive heart failure

Central Nervous System: Suicidal tendency, headache, dizziness, convulsions, depression, lack of sleep, confusion, weakness, slurred speech, fearful feelings, and thoughts

Skin: Rashes, skin allergies, lichenoid eruptions and Stevens Johnson Syndrome

Other Precautions : • Usage of high doses such as more than 1g a day is not recommended because of the occurrence of liver disease, congestive cardiac failure, convulsions, and coma.

Drug Name : Terizidone

Terizidone(Terivalidin) generic Terizidone is a second-line antitubercular drug which is prescribed for the treatment of both pulmonary and extra pulmonary tuberculosis caused by resistant strains of Mycobacterium tuberculosis or M. avium. Pulmonary tuberculosis is limited to the lungs, while extra-pulmonary tuberculosis refers to the infection at other sites of the body. Terizidone is used in multi-drug resistant and extensively drug-resistant tuberculosis. Terizidone is effective against Mycobacterium strains which are resistant to first-line drugs both in intensive and continuation phase. It is not recommended to be used as a single drug in treating tuberculosis, or for other infections despite being a broad-spectrum antibiotic. Terizidone is a drug of choice in treating urogenital tuberculosis such as cystitis (bladder infection) or epididymoorchitis (infection of the testes in males). Terizidone has a similar effect as cycloserine and inhibits the bacterial wall synthesis. It, however, has lesser side effects including low blood pressure and has an advantage of treating tuberculosis patients with schizophrenia and alcoholics. It has been found more useful in treating drug-resistant cases of TB which require dialysis.
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