Side effect(s) of Tegafur and Uracil

Read the side effects of Tegafur and Uracil as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Gastrointestinal: Diarrhea, nausea, vomiting, stomatitis, stomach pain, loss of appetite

Nervous system: Nerve pain, neuropathy, burning or prickling sensation in the hands and feet, speech disturbances

Cardiovascular: Blood clots, heart attack, chest pain

Skin: Hair loss, rashes, itching, eczema, leukoderma

Others: Bone marrow suppression, weakness, anemia, abnormal values of white blood cells and platelets, liver damage, loss of control in balance

Other Precautions : The treatment with tegafur-uracil can be stopped temporarily and resumed once the side effects are significantly reduced and the abnormal blood cell counts return to near normal limits.

Treatment discontinuation of tegafur-uracil is usually not recommended because most of the side effects are reversible when the dose of tegafur-uracil is reduced or withheld.

Wash the skin or flush the eyes thoroughly with clean water if the capsule contents of tegafur-uracil come into contact with the skin or eyes.

There are no specific antidotes available for treating an overdose of tegafur-uracil. So, patients with such episodes must be treated appropriately for the symptoms and signs along with supportive care under the supervision of a toxicologist or a specialist.
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