Sofosbuvir and Velpatasvir generic The sofosbuvir and velpatasvir combination is an antiviral drug combination that is prescribed for the treatment of chronic hepatitis C infections. Sofosbuvir and velpatasvir belong to the nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitor and HCV NS5A replication complex inhibitor groups, respectively. The combination is used with or without ribavirin for the treatment of chronic hepatitis C infections of genotype 1, 2, 3, 4, 5 and 6. The drug combination stops the replication of the HCV virus.
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