Review the side-effects of Sofosbuvir as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Nausea, loose stools, loss of appetite, vomiting, constipation
Nervous system: Headache, fever, irritability, inability to sleep, attention deficit disorder
Respiratory: Cough, flu symptoms, breathing difficulty
Lab abnormalities: Abnormal levels of hemoglobin, neutrophils, platelets, bilirubin, creatine kinase and lipase
Others: Rashes, itching, muscle pain, chills, weight loss, blurred vision
There is no specific antidote for treating sofosbuvir overdosage. Patients who are overdosed with sofosbuvir must be provided with general supportive measures under the supervision of a medical specialist.
Hemodialysis is also recommended as 4-hour dialysis can remove approximately 18 percentage of the given dose.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Nausea, loose stools, loss of appetite, vomiting, constipation
Nervous system: Headache, fever, irritability, inability to sleep, attention deficit disorder
Respiratory: Cough, flu symptoms, breathing difficulty
Lab abnormalities: Abnormal levels of hemoglobin, neutrophils, platelets, bilirubin, creatine kinase and lipase
Others: Rashes, itching, muscle pain, chills, weight loss, blurred vision
Other Precautions :
If ribavirin or peginterferon alfa is discontinued for any reasons, sofosbuvir should also be discontinued.There is no specific antidote for treating sofosbuvir overdosage. Patients who are overdosed with sofosbuvir must be provided with general supportive measures under the supervision of a medical specialist.
Hemodialysis is also recommended as 4-hour dialysis can remove approximately 18 percentage of the given dose.
