Side effect(s) of Primaquine

Read the side effects of Primaquine as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Gastrointestinal:Pain in the stomach, heartburn, nausea and vomiting

Eye: Blurred vision

Cardiovascular system: Fast, slow or irregular heartbeat (prolonged QT interval may be noted on ECG)

Blood: Reduced white blood counts. Hemolysis may occur especially in patients with G6PD enzyme deficiency. The patient may present with yellow discoloration of eyes, dark colored urine, pale lips or skin, shortness of breath, and dizziness. Methemoglobinemia may also occur with symptoms of grayish discoloration of the skin and lips, headache, fatigue and chestpain

Allergic reaction: Rashes, itching



Other Precautions : • Blood cell counts and hemoglobin levels should be monitored regularly as anemia, leucopenia, and methemoglobinemia could occur during the therapy.
• Since G6PD test assay is widely not available, due to the risk of hemolysis (rupturing of red blood cell), adequate medical support and follow-up should always be available.
• ECG monitoring is required particularly in patients with heart illness as primaquine can result in abnormal heart rhythm.
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