Side effect(s) of Panobinostat

Read the side effects of Panobinostat as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Gastrointestinal: Diarrhea, fatigue, nausea, peripheral edema (accumulation of water), decreased appetite, and vomiting.

Hematological: low platelet count), low white blood cell count, anemia (low Hemoglobin), low phosphorous, potassium levels in the blood.

Nervous system: dizziness, headache , syncope (fainting), dysgeusia (altered taste)

Cardiovascular: palpitations (increased heart rate)

Respiratory: cough , dyspnea, respiratory failure, wheezing (abnormal lung sounds)

Vascular system: hypotension (low blood pressure), hypertension (High blood pressure)

Skin and subcutaneous disorders: skin rash, erythema (redness of skin)

Musculoskeletal disorders: joint swelling.

Renal and urinary disorders: Kidney failure, urinary incontinence (uncontrolled leak of urine)

General disorders and administration site conditions: chills.

Lab monitoring: blood urea, glomerular filtration rate, blood alkaline phosphatase levels should be monitored.

Other Precautions :  Women in reproductive age should use effective contraception until 1 month of the last dose of panobinostat.
Men should use condoms for at least 3 months of the last dose of panobinostat.
Panobinostat capsules contact with the skin or mucous membranes should be avoided. Wash thoroughly if such contact occurs.
Exposure to crushed and/or broken capsules should be avoided.
Keep away from children.
Patients should report chest pain or discomfort or changes in heartbeat, fever, swelling in legs, hands and skin, diarrhea, bleeding, immediately to consulting doctor.
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