Review the
side-effects of Palbociclib as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your
doctor or pharmacist.
General: Fatigue
Gastrointestinal: Nausea, vomiting, diarrhea, decreased appetite, stomatitis (inflammation of the mucus membrane of the mouth).
Respiratory: Shortness of breath, sudden chest pain due to pulmonary embolism, bleeding from the nose (epistaxis).
Blood: Reduced counts of blood cells i.e. red blood cells, white blood cells and platelets.
Nervous system: Peripheral neuropathy (damage to the peripheral nerves).
Hair: Unusual thinning of hair or hair loss.
Other Precautions : • Do not breastfeed your baby while taking palbociclib as there is no clear data on whether the drug could pass through the breastmilk and harm the baby.
• Patients should be advised to avoid grapefruit juice while taking the drug as it might increase the plasma concentration of the drug.
• It is advisable that the patient does not take an extra dose of palbociclib on the same day if he/she vomits or misses the dose on that day.
