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Side effect(s) of Obinutuzumab


Review the side-effects of Obinutuzumab as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Gastrointestinal:
Diarrhea, constipation, indigestion, loss of appetite

  Nervous system:
Dizziness, confusion, difficulty in speech or to walk, loss of balance

  Respiratory:
Cough, nasal congestion, sneezing, inflammation of the sinuses, nasopharyngitis

  Musculoskeletal:
Joint pain, pain in the extremities, muscle pain or cramps

  Blood:
Low levels of neutrophils, lymphocytes, white blood cells

  Lab abnormalities:
Decreased levels of calcium, potassium, sodium, and phosphate in the blood, increased liver enzymes, and creatinine levels

  Others:
Headache, itching, fever, weakness, vision problems

Other Precautions :

Breastfeeding mothers should be advised not to breastfeed their babies during and 18 months after the obinutuzumab treatment is stopped.

Women of reproductive potential living with active male partners should follow an effective contraceptive measure during obinutuzumab treatment and must continue the contraception for at least 18 months after the last dose of obinutuzumab.

Inspect the obinutuzumab vials and the diluted solution for the presence of any visible solid matter or discoloration before administering it to the patient.

Drug Name : Obinutuzumab

Obinutuzumab is prescribed to treat chronic lymphocytic leukemia (CLL) in combination with chlorambucil and to treat follicular lymphoma (FL) either alone or in combination with bendamustine in adult patients whose cancer has not responded to previous chemotherapy.


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