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Side effect(s) of Nusinersen

Read the side effects of Nusinersen as described in the medical literature. In case of any doubt consult your doctor or pharmacist.

Respiratory System: Respiratory tract infections, difficulty in breathing

Blood: Reduced platelet count, problems with blood clotting

Kidneys: Possible kidney damage

ENT: Ear infection

Gastrointestinal System: Constipation

Central Nervous System: Scoliosis (sideways curving of the spine).

Other Precautions :  Nusinersen injection may increase the risk of bleeding. Therefore it is essential to perform blood tests for platelet count and clotting at the baseline before each dose of the drug to monitor for early signs.
Do not administer the injection if there is a presence of any particular matter or discoloration.
Check the urine for protein for any indication of renal toxicity

Drug Name : Nusinersen

Nusinersen generic Nusinersen is a survival motor neuron (SMN-2) directed antisense oligonucleotide which is prescribed for the treatment of spinal muscular atrophy (SMA) in children and adults. Spinal muscular atrophy is a genetic disease which affects the nervous system and causes weakness of muscles under voluntary control. Oligonucleotides are small strands of DNA or RNA that can bind to specific molecules of RNA. Nusinersen increases the production of SMN protein, which is deficient in these patients.
More Info about Nusinersen


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