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Side effect(s) of Nivolumab


Review the side-effects of Nivolumab as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Respiratory:
Persistent cough, chest pain, breathing difficulties.

  Gastrointestinal:
Diarrhea, nausea, vomiting, abdominal pain, blood in the stools, dark or black stools, loss of appetite.

  Endocrine glands:
Headache, tiredness, dizziness, weight gain or weight loss, hair loss, excessive thirst, decreased interest in sexual activity.

  Skin problems:
Rash, itching, blistering of the skin, losing color in the skin and hair, mouth sores and ulcers.

  Kidney problems:
Decreased or increased production of urine, swelling of the ankles, increased thirst and blood in the urine.

  Central nervous system:
Brain inflammation which might result in memory problems, confusion, hallucinations, seizures, headaches, tiredness, fever or stiff neck.Nerve problems resulting in paralysis, weakness, numbness or tingling in hands and the feet.

  Eye problems:
Blurred vision, eye pain or redness.

Other Precautions :

• Do not use nivolumab for children /individuals below 18 years of age as the safety and efficacy of the drug in this population is not clearly known.
• Nivolumab infusion might lead to serious life-threatening conditions, therefore the patient should be monitored by a doctor or nurse while taking the infusion.

Drug Name : Nivolumab

Nivolumab generic Nivolumab is a monoclonal antibody and a PD-1 inhibitor (programmed death receptor inhibitor) which is prescribed for cancer treatment. It is mainly used for treating progression or relapse of classical Hodgkin lymphoma (a type of blood cancer), and melanoma (a skin cancer) which has spread to other parts of the body and which cannot be removed by surgery. It is also used as a second-line treatment for non-small cell lung cancer and renal cell carcinoma (kidney cancer) which worsens during or after treatment with other chemotherapy medications. The mode of action involves slowing down or stopping the growth of cancer cells by working with the immune system (immune checkpoint blockade).



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